Multiparameter Fiber Optic Breathing Sensor

多参数光纤呼吸传感器

• 批准号: 7746998
• 负责人: EDGAR A MENDOZA
• 金额: $ 15万
• 依托单位: REDONDO OPTICS, INC.
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2010-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7746998
• 关键词: Acute; Adult; Affect; Air; American; American Hospital Association; Apnea; Apparent Life Threatening Event; Arts; Asthma; Attention; Autopsy; Back; Behavior; Blood; Breathing; Capnography; Carbon Dioxide; Caring; Categories; Cellular Phone; Cessation of life; Child; Childhood; Chronic; Chronic Care; Clinical; Clinical Trials; Communication; Data; Data Storage and Retrieval; Detection; Device Designs; Devices; Diabetes Mellitus; Diagnosis; Disease; Doctor of Medicine; Ear; Ear lobe; Early Diagnosis; Electric Wiring; Electrocardiogram; Electromagnetics; Electronics; Equipment; Event; Exhalation; Fiber Optics; Gases; Glass; Gold; Growth; Head; Hearing Aids; Heart Diseases; Home environment; Hospitals; Human Resources; Humidity; Hypoxemia; Infant; Infant Behavior; Infant Mortality; Knowledge; Laboratories; Life; Light; Los Angeles; Lower respiratory tract structure; Lung; Marketing; Measurement; Medical; Medical Device; Medicine; Monitor; Motion; Nose; Obstruction; Obstructive Sleep Apnea; Operative Surgical Procedures; Optics; Oral; Oral cavity; Oxygen; Parents; Patient Monitoring; Patient Monitoring System; Patients; Performance; Personal Computers; Persons; Phase; Physiologic pulse; Plastics; Preventive; Price; Reaction Time; Recommendation; Research; Resolution; Respiration Disorders; Risk; Safety; Semiconductors; Signal Transduction; Sleep; Solutions; Source; Stress; Structure; Sudden infant death syndrome; Supervision; Syndrome; System; Technology; Temperature; Testing; Time; Tube; Viral; Wireless Technology; base; computerized data processing; cost; design; detector; electric impedance; falls; high risk; improved; infancy; innovative technologies; instrumentation; microchip; monitoring device; mortality; optical fiber; optical sensor; phantom model; physical property; premature; programs; prototype; public health relevance; research and development; research clinical testing; respiratory; respiratory gas; sensor; sound; user-friendly; wireless network

DESCRIPTION (provided by applicant): There is a need to develop devices for the detection of periodic breathing, or brief (<20- seconds) central or obstructive apnea, associated with hypoxemia for infants at risk of sudden infant death syndrome (SIDS). A non-intrusive, cost-effective, reliable, and user-friendly breathing monitor can improve the safety and reduce mortality risk to infants, children, and adults suffering from acute and viral respiratory disorders. For this reason, Redondo Optics, Inc., (ROI), a leader in the research and development of advanced optical medical diagnosis instrumentation, proposes to develop a new, highly accurate and reliable, low-cost, portable, and non-invasive, ResHealth" device for monitoring breathing activity in clinical high risk, life threatening, conditions associated with hypoxemia in infants and children suffering from central or obstructive apnea or at risk of sudden infant death syndrome (SIDS), and other acute respiratory breathing disorders. In Phase I of this program, ROI will conclusively demonstrate the concept of the ResHealth" monitoring device by designing, assembling, and testing a conceptual prototype of a non intrusive multi-sensor array optical microchip, and optoelectronic sensor readout unit capable of detecting, analyzing, and separating vital breathing activity signatures, and to generate an alarm in the case of a potential catastrophic event with higher sensitivity, selectivity, and with near false alarms, that conventional monitoring systems. In Phase II, ROI will integrate the ResHealth" monitoring device into a portable, stand-alone unit. Such a system will find an immediate use in the fast growing breathing monitors and diagnosis market. No other available commercial device in the market today offers such capabilities at an affordable cost. PUBLIC HEALTH RELEVANCE: In this Phase I, Redondo Optics will design and develop a small, cost-effective, disposable, wireless multi-sensor chip for monitoring breathing activity. The proposed sensor will permit assessment of vital breathing function associated with hypoxemia in infant and children suffering from central or obstructive apnea or SIDS and could decrease costs by reducing the need for more costly central facility.

描述（由申请人提供）：需要开发用于检测有婴儿猝死综合征（SIDS）风险的婴儿低氧血症相关的周期性呼吸或短暂（<20秒）中央性或阻塞性呼吸暂停的设备。一种非侵入性、成本效益高、可靠且用户友好的呼吸监测仪可以提高患有急性和病毒性呼吸疾病的婴儿、儿童和成人的安全性并降低死亡风险。为此，先进光学医疗诊断仪器研究和开发的领导者Redondo Optics， Inc. （ROI）提议开发一种新的，高度准确和可靠的，低成本，便携式和无创的rehealth”设备，用于监测临床高风险，危及生命的，与低氧血症相关的婴儿和患有中心性或阻塞性呼吸暂停或婴儿猝死综合征（SIDS）风险的儿童的呼吸活动。以及其他急性呼吸系统疾病。在该计划的第一阶段，ROI将通过设计、组装和测试非侵入式多传感器阵列光学微芯片的概念原型，以及能够检测、分析和分离重要呼吸活动特征的光电传感器读出单元，最终演示rehealth”监测设备的概念，并在潜在灾难性事件的情况下以更高的灵敏度、选择性和接近假警报生成警报。那就是传统的监控系统。在第二阶段，ROI将把rehealth监控设备集成到一个便携式的独立设备中。这种系统将在快速增长的呼吸监测和诊断市场中立即得到应用。目前市场上没有其他可用的商用设备以可承受的成本提供这样的功能。公共卫生相关：在第一阶段，Redondo Optics将设计和开发一种小型、经济高效、一次性的无线多传感器芯片，用于监测呼吸活动。该传感器将允许评估患有中枢性或阻塞性呼吸暂停或SIDS的婴儿和儿童与低氧血症相关的重要呼吸功能，并可以通过减少对更昂贵的中心设施的需求来降低成本。