CENTER FOR COMPUTATIONAL BIOLOGY & BIOINFORMATICS (CCBB)

计算生物学中心

• 批准号: 8166193
• 负责人: William M. Southerland
• 金额: $ 85.31万
• 依托单位: HOWARD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8166193
• 关键词: Area; Arts; Biocompatible Materials; Bioinformatics; Biomedical Research; Cell physiology; Communities; Computational Biology; Computer Retrieval of Information on Scientific Projects Database; Computer software; Databases; Development; Funding; Gene Proteins; Genetic; Grant; Human; Human Resources; Institution; Internet; Investigation; Laboratories; Ligands; Protein Sequence Analysis; Proteomics; Research; Research Personnel; Research Support; Resources; Scientist; Screening procedure; Source; Therapeutic Agents; Training; United States National Institutes of Health; Universities; Update; base; computational chemistry; design; improved; member; method development; simulation; virtual

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Howard University Center for Computational Biology and Bioinformatics (CCBB) is a resource facility dedicated to the support of computational biology and bioinformatics research at Howard University. The objective of the laboratory is to provide support for research in the following areas: 1) bioinformatics and statistical genetics, 2) macromolecular analysis and simulation, 3) virtual ligand screening and database development, 4) computational chemistry, and 5) computational proteomics and methods development. It is proposed to maintain and update the computational capabilities of the center (i.e., hardware and software resources) while also maintaining its human resources. These requests are commensurate with the increased number of CCBB users and with the increased complexity and diversity of projects that are being undertaken. The facility will also continue to make available to the Howard University community of scientists the necessary human, software, and hardware resources to perform successful and competitive computational biomedical research. CCBB users have remote access to CCBB resources via the internet. Scientists from the national RCMI community will also have internet-based access to CCBB resources. It is also proposed to provide enhanced technical support to the growing cadre of users who access CCBB resources remotely. It is proposed to provide user training on the use of CCBB software. As a result of these plans, state-of-the-art computational biology and bioinformatics research resources will be available to both the Howard University community of scientists and to members of the national RCMI community. Access to these kinds of resources will be increasingly important in the pursuit of investigations on gene and protein sequence analysis, the design and development of new and improved therapeutic agents, biomolecules and biomaterials, and a better understanding of cellular processes.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 霍华德大学计算生物学与生物信息学中心（CCBB）是一种资源设施，致力于支持霍华德大学计算生物学和生物信息学研究。 该实验室的目的是在以下领域提供支持：1）生物信息学和统计遗传学，2）大分子分析和模拟，3）虚拟配体筛选和数据库开发，4）计算化学和5）计算蛋白质组学和方法的开发。 建议维护和更新中心的计算能力（即硬件和软件资源），同时还维护其人力资源。 这些请求与CCBB用户数量的增加以及正在进行的项目的多样性相称。 该设施还将继续向霍华德大学科学家社区提供必要的人，软件和硬件资源，以执行成功和竞争性的计算生物医学研究。 CCBB用户可以通过Internet远程访问CCBB资源。 来自国家RCMI社区的科学家还将基于Internet访问CCBB资源。 还建议为远程访问CCBB资源访问CCBB资源的越来越多的用户提供增强的技术支持。 建议提供有关使用CCBB软件的用户培训。 这些计划的结果是，霍华德大学科学家和国家RCMI社区的成员将获得最先进的计算生物学和生物信息学研究资源。 在追求基因和蛋白质序列分析，新的和改进的治疗剂，生物分子和生物材料的设计和开发以及对细胞过程的更好理解的研究和开发方面，获得这些资源将越来越重要。