CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCH

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这是佛罗里达大学(UF)首次修订CTSA申请。佛罗里达大学(UF)拥有丰富的环境，拥有一流的学院、最先进的研究设施以及全州范围的健康教育和健康提供系统。这些资源使UF处于培训下一代临床和转化型研究人员的机构的前沿，并帮助克服我国临床研究事业中的两大障碍：将基础科学发现转化为人类早期研究，以及将临床研究转化为更好的医疗实践和保健提供。UF已经进行了大量的投资，专门用于完成这些任务。此外，为了直接响应临床和转化科学奖的倡议，它投入了大量新的研究和培训资源，并对其传统的报告、研究和培训业务进行了重大重组，以创建一个跨机构的临床和转化科学研究所(CTSI)。该研究所将为密歇根大学的临床和翻译研究和培训提供新的智力家园，整合和协同12所学院、两个学术和临床校区、两个地区医疗系统和佛罗里达州67个县的科学和教育活动。因此，该提案提出了在实施机构CTSA计划时要实现的以下目标：1)创造一个环境，通过这个环境，来自不同学科的个人可以互动，可以确定和获得资源、服务和技术，并可以克服合作研究的本地和地区障碍；2)培训一支临床和基础科学研究人员、临床试验人员、实验室技术人员、研究协调员和其他相关人员的队伍，他们需要建立和支持多学科和跨学科的临床和翻译研究团队3)提高尖端技术和新研究计划的质量和可用性，以加速新的诊断和治疗模式的发现、开发和应用；以及4)为临床科学家和佛罗里达州公民创造新的机会，共同推进人类疾病的病因、预防、诊断、治疗和治愈方面的教育和研究。相关性(参见说明)：该提案与UF转变其开展多学科和跨学科临床和转化性研究和培训的方式以及使佛罗里达州公民参与基于社区的参与性研究、教育、医疗保健和医疗保健提供的方式相关。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is the first revision of the application by the University of Florida (UF) for a CTSA. The University of Florida (UF) has a rich environment of distinguished colleges, state-of-the-art research facilities and statewide health education and health delivery systems. These resources position UF at the forefront of institutions to train the next generation of clinical and translational investigators and to help overcome two major obstacles in our nation's clinical research enterprise: the translation of basic science discoveries to early investigations in humans and the translation of clinical research into better medical practice and healthcare delivery. UF has made considerable investments dedicated exclusively to accomplish these missions. Furthermore, in direct response to the Clinical and Translational Science Award initiative, it committed substantial new research and training resources and undertook major restructuring of its traditional reporting, research and training operations to create a trans-institutional Clinical and Translational Science Institute (CTSI). The Institute will provide the new intellectual home for clinical and translational research and training at UF, integrating and synergizing the scientific and educational activities of 12 colleges, two academic and clinical campuses, two regional healthcare systems and the 67 counties ofthe State of Florida. Accordingly, this proposal sets forth the following goals to be accomplished in implementing the Institutional CTSA program: 1) Create an environment through which individuals from diverse disciplines can interact, resources, services and technologies can be identified and accessed and local and regional barriers to collaborative research can be overcome; 2) Train a workforce of clinical and basic science investigators, clinical trialists, laboratory technicians, study coordinators and other related personnel who are required to establish and support multi- and interdisciplinary clinical and translational research teams3 3) Enhance the quality and availability of cutting-edge technologies and novel research programs to accelerate the discovery, development and application of new diagnostic and therapeutic modalities; and 4) Create new opportunities for clinical scientists and the citizens of Florida to collaborate in advancing education and research into the causes, prevention, diagnosis, treatment and cure of human disease. RELEVANCE (See instructions): The proposal is relevant to the ability of UF to transform the manner by which it conducts multi- and interdisciplinary clinical and translational research and training and by which it engages the citizens across the State of Florida in community-based participatory research, education, health care and health care delivery.