DETERMINING AQUATIC BIOINDICATORS FOR ATRAZINE

测定阿特拉津的水生生物指示剂

• 批准号: 7960201
• 负责人: ANDRE W DELORME
• 金额: $ 19.32万
• 依托单位: UNIVERSITY OF NORTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-10 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7960201
• 关键词: Address; Agriculture; Area; Atrazine; Chemicals; Computer Retrieval of Information on Scientific Projects Database; Data; Ecosystem; Endocrine Disruptors; Environment; Funding; Goals; Grant; Health; Herbicides; Human; Institution; Investigation; North Dakota; Organism; Phase; Prevalence; Procedures; Research; Research Personnel; Resources; Rivers; Route; Source; Stream; Surface; System; Testing; Toxicity Tests; United States National Institutes of Health; Water; aquatic organism; water testing

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The long-term goal of this project is to examine the possible effects of atrazine and its metabolites on aquatic macroinvertebrates found in streams and rivers in North Dakota. Atrazine is a commonly used herbicide that persists in aquatic systems and has recently been shown to act as an endocrine disrupter in a variety of organisms. There is currently little research being done in North Dakota on atrazine in aquatic systems. In addition, there is a need for more data on the effects of this herbicide on aquatic organisms. The popular approach to toxicity testing is to perform single species tests in a controlled microcosm and then extrapolate the results to natural occurring environments. Often the species examined are those that have been easily cultured in past testing and may not have any relationship to the species occurring in local aquatic ecosystems. This approach has been criticized because of its artificiality. We will take a different approach, we will use field collected data to determine which species should be considered for toxicity testing. Local species and conditions will be considered in all phases of our investigations. This study will investigate several areas of concern regarding atrazine in aquatic systems. It will address the prevalence of atrazine in aquatic systems, examine this prevalence with the known macroinvertebrate fauna, identify aquatic macroinvertebrate fauna that may be indicative of atrazine contamination, and examine what effects atrazine may have on aquatic macroinvertebrates. Because of atrazine's action as an endocrine disrupter in mammalian systems, there is considerable concern with the possible implications exposure may have on human systems. Atrazine is widespread and a common component of surface waters in agricultural areas. Current water testing procedures require extensive chemical analysis. The discovery of a bioindicator for atrazine contamination would be beneficial in documenting possible exposure routes for atrazine to humans. 

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 该项目的长期目标是研究阿特拉津及其代谢物对北达科他州溪流和河流中发现的水生大型无脊椎动物的可能影响。阿特拉津是一种常用的除草剂，在水生系统中持续存在，最近被证明在各种生物体中起内分泌干扰物的作用。目前，北达科他州对阿特拉津在水生系统中的研究很少。此外，还需要更多关于这种除草剂对水生生物影响的数据。 毒性测试的流行方法是在受控的微观世界中进行单一物种测试，然后将结果外推到自然发生的环境中。通常被检查的物种是那些在过去的测试中很容易养殖的物种，可能与当地水生生态系统中出现的物种没有任何关系。这种方法因其矫揉造作而受到批评。我们将采取一种不同的方法，我们将使用现场收集的数据来确定哪些物种应该被考虑进行毒性测试。我们在调查的所有阶段都会考虑当地的物种和条件。 这项研究将调查有关阿特拉津在水生系统中的几个令人担忧的领域。它将解决阿特拉津在水生系统中的流行率，用已知的大型无脊椎动物来检查这一流行率，确定可能表明阿特拉津受到污染的水生大型无脊椎动物，并研究阿特拉津对水生大型无脊椎动物可能产生的影响。 由于阿特拉津在哺乳动物系统中作为内分泌干扰物的作用，人们对暴露可能对人类系统产生的影响有相当大的担忧。阿特拉津广泛存在，是农业地区地表水的常见成分。目前的水测试程序需要广泛的化学分析。阿特拉津污染生物指示剂的发现将有助于记录阿特拉津对人类的可能接触途径。