BIOMETRY CORE

生物测量核心的目标是为所有项目提供数据管理和计算支持， 并与项目调查人员合作，开发和应用统计方法 设计和分析。这一目标是通过以下具体目标实现的： 1.提供实验室和临床研究的统计设计和审查，包括可行性评估 和样本量估计。 2.制定收集数据的程序，并维护计算机数据库以储存信息 和取回。 3.在所有方案项目研究的执行和分析方面提供统计合作。 4.解读与所有项目相关的统计和临床文献，并开发新的研究设计 和数据分析程序，以满足计划项目目标。 计划项目研究的所有阶段都需要生物测量学支持。在研究设计期间，核心将 解决统计权力和样本大小问题，并将与研究调查人员合作建立数据 管理程序。研究完成后，核心执行统计分析，与 研究人员。核心人员还将准备和协助编写手稿 出版。生物测量核心继续由两个实验室的所有计划项目调查人员使用 和临床环境。

The objective of the Biometry Core is to provide data management and computing support for all projects, and to collaborate with project investigators in the development and application of statistical methods for design and analysis. This goal is achieved through the following specific aims: 1. To provide statistical design and review of laboratory and clinical studies including feasibility assessment and sample size estimation. 2. To develop procedures for data collection and to maintain computer databases for information storage and retrieval. 3. To provide statistical collaboration in the execution and analysis of all program project studies. 4. To interpret the statistical and clinical literature relevant to all projects, and to develop new study design and data analysis procedures to meet program project objectives. Biometry support is required in all phases of program project studies. During study design the core will address statistical power and sample size issues, and will work with study investigators to establish data management procedures. Upon study completion, the core performs statistical analyses in collaboration with study investigators. Core personnel will also prepare and assist in the preparation of manuscripts for publication. The Biometry Core continues to be used by all program project investigators in both laboratory and clinical settings.