Pilot Project

生物库在癌症研究中的作用。卫生研究人员和行业越来越多地认识到生物库的价值及其与病历数据、表型信息和社会人口数据的联系(93)。生物库是遗传和公共卫生研究的基本资源，包括研究基因类型之间的联系、环境暴露的衡量标准以及了解 遗传学与疾病易感性(92)。生物库通常从两个不同的群体收集标本：(1)普通公众和(2)特定疾病人群。普通人群生物库的主要目标是在大量具有代表性的健康人群中识别疾病易感性的生物标志物和遗传标志物。以疾病为导向的生物库专注于识别暴露的生物标记物和tjiomarks。 疾病，如结直肠癌(94)。一些生物库针对的是妇女或地理区域等亚群体(92)。世界各地都有大小不一的生物库，它们通常由政府实体提供资金(91)。

Role of Biobanks in Cancer Research. Increasingly, health researchers and industry are realizing the value of biobanks and their linkages to medical record data, phenotypic information, and sociodemographic data (93). Biobanks serve as essential resources for genetic and public health research, including studies of associations between genotypes, measures of environmental exposures, and understanding the role of genetics in disease susceptibility (92). Biobanks generally collect specimens from two distinct groups: (1) the general public and (2) disease-specific populations. The primary goal of the general population biobank is to identify biomarkers and genetic markers for disease susceptibility among a large, representative population of healthy people. The disease-orientated biobanks focus on identifying biomarkers of exposure and tjiomarkers of disease, such as colorectal cancer (94). Some biobanks target sub-populations like women or geographical regions (92). Biobanks of varying size are found all over the world and they are often funded by government entities (91).