Pilot Project

生物库在癌症研究中的作用。越来越多的健康研究人员和行业正在认识到生物库的价值及其与医疗记录数据，表型信息和社会人口数据的联系（93）。生物库是遗传和公共卫生研究的重要资源，包括研究基因型之间的关联，环境暴露的测量，以及了解 疾病易感性的遗传学（92）。生物库通常从两个不同的群体收集标本：（1）一般公众和（2）疾病特异性人群。一般人群生物库的主要目标是在大量有代表性的健康人群中识别疾病易感性的生物标志物和遗传标志物。以疾病为导向的生物库侧重于识别暴露的生物标志物和 疾病，如结肠直肠癌（94）。一些生物库针对女性或地理区域等亚人群（92）。世界各地都有不同规模的生物库，它们通常由政府实体资助（91）。

Role of Biobanks in Cancer Research. Increasingly, health researchers and industry are realizing the value of biobanks and their linkages to medical record data, phenotypic information, and sociodemographic data (93). Biobanks serve as essential resources for genetic and public health research, including studies of associations between genotypes, measures of environmental exposures, and understanding the role of genetics in disease susceptibility (92). Biobanks generally collect specimens from two distinct groups: (1) the general public and (2) disease-specific populations. The primary goal of the general population biobank is to identify biomarkers and genetic markers for disease susceptibility among a large, representative population of healthy people. The disease-orientated biobanks focus on identifying biomarkers of exposure and tjiomarkers of disease, such as colorectal cancer (94). Some biobanks target sub-populations like women or geographical regions (92). Biobanks of varying size are found all over the world and they are often funded by government entities (91).