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AIM-HIGH CAROTID MRI STUDY

AIM-HIGH CAROTID MRI STUDY
AIM-高颈动脉 MRI 研究
批准号：
8167035
负责人：
JOHN R CROUSE
金额：
$3.35万
依托单位：
WAKE FOREST UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-03-01 至 2011-02-28
来源：
https://reporter.nih.gov/project-details/8167035
关键词：
ArteriesCarotid ArteriesCessation of lifeClinicalClinical TrialsComputer Retrieval of Information on Scientific Projects DatabaseDimensionsFundingGrantHigh Density LipoproteinsInstitutionMagnetic Resonance ImagingOutcomeResearchResearch PersonnelResourcesSourceStrokeUnited States National Institutes of Healthin vivo

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中文摘要
翻译
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 AIM-HIGH MRI子研究将提供高密度脂蛋白增加对颈动脉尺寸和组成的影响的无创体内量化。这些动脉水平的影响将与临床结局（如MI、卒中和CHD死亡）进行比较。这些比较将使我们能够评估MRI作为临床试验的非侵入性终点。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The AIM-HIGH MRI Substudy will provide non-invasive in vivo quantification of the effect of increasing HDL on carotid artery dimensions and composition. These artery level effects will be compared to clinical outcomes such as MI, stroke and CHD death as well. These comparsions will allow us to evaluate MRI as a non-invasive endpoint for clinical trials.
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CLINICAL TRIAL: AIM-HIGH: ATHEROSCLEROSIS INTERVENTIONIN MATABOLIC SYNDROME WIT
CLINICAL TRIAL: ACTION TO CONTROL CARDIOVASCULAR RISKS IN DIABETES (ACCORD)
CLINICAL TRIAL: ACTION TO CONTROL CARDIOVASCULAR RISKS IN DIABETES (ACCORD)
AIM-HIGH CAROTID MRI STUDY
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