CARDIAC RESYNCHRONIZATION THERAPY AND THE SKELETAL MYOPATHY OF HEART FAILURE

心脏再同步治疗和心力衰竭的骨骼肌病

• 批准号: 8167111
• 负责人: HOLLY R MIDDLEKAUFF
• 金额: $ 0.07万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8167111
• 关键词: Cardiac; Cardiopulmonary; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Heart failure; Institution; Mechanoreceptors; Muscle; Myopathy; Patients; Pressoreceptors; Research; Research Personnel; Resources; Rest; Source; United States National Institutes of Health; receptor; skeletal

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. 1.1 Does CRT reduce resting MSNA chronically in advanced HF? 1.2 Is the skeletal myopathy reversed in HF patients in whom MSNA is decreased following CRT? 1.3 Does an increase in arterial baroreceptor and cardiopulmonary receptor gain underlie this decrease in MSNA following CRT? 1.4 Does reversal of the augmented muscle mechanoreceptor sensitivity in HF contribute to the decrease in MSNA following CRT?

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 1.1晚期心力衰竭患者CRT是否会慢性降低静息MSNA？ 1.2 CRT治疗后MSNA降低的心衰患者骨骼肌病是否逆转？ 1.3动脉压力感受器和心肺感受器增益的增加是否是CRT后MSNA下降的原因？ 1.4高频时增强的肌肉机械感受器敏感性的逆转是否有助于CRT后MSNA的下降？