NICHD Institutional Training for Pediatricians (T32)

描述（由申请人提供）：该机构NRSA的长期目标是培养新一代的儿科专家在翻译和实验室研究。培训经验的重点将是分子和转化医学，定义为使用复杂的分子方法来改善儿科疾病的诊断和治疗。 该计划实际上位于全国儿童医院的校园内，该医院是全国儿童医院研究所和俄亥俄州州立大学医学院儿科系的学术所在地。近年来，我们的研究机构投入了大量资源。 研究所独特地组织成重点中心，有目的地消除传统的基于学术部门的研究孤岛，并根据科学兴趣和需求调整研究人员和受训人员。这种独特的组织模式允许儿科采用本文所述的新方法进行亚专业研究培训。简而言之，每个中心都将作为研究员的培训单位和科学界。除了传统的指定教师导师模式外，对个别研究员的科学培训和指导将由选定的培训单位（中心）及其教师负责。 利用这种独特的模式，我们在前5年的融资中取得了巨大成功。我们建议更新这个NRSA，并计划在下一个奖励期内培养总共8名MD或MD/PhD儿科科学家。一个有才华的高级医学博士骨干。和博士科学家们热情地同意担任项目教员。我们独特的培训模式，结合组织承诺建立一流的研究基础设施，使全国儿童医院处于有利地位，提供最高水平的亚专业研究培训计划。 公共卫生相关性：生物医学研究的最新进展为通过分子方法预防和治疗儿童疾病的进展创造了非凡的机会。一个主要障碍是缺乏训练有素的儿科医生科学家队伍。这项培训补助金旨在积极培养一批优秀的儿科科学家，以满足对新人才的迫切需求。

DESCRIPTION (provided by applicant): The long-term objective of this Institutional NRSA is to train a new generation of pediatric subspecialists in translational and laboratory research. The focus of the training experience will be molecular and translational medicine, defined as the use of sophisticated molecular approaches to improve diagnosis and treatment of pediatric diseases. The program is physically located on the campus of Nationwide Children's Hospital, the academic home of both The Research Institute at Nationwide Children's Hospital and the Department of Pediatrics in the College of Medicine at The Ohio State University. In recent years, there has been a substantial resource commitment to research at our institution. The Research Institute is uniquely organized into Centers of Emphasis, which purposefully dissolve the traditional academic division-based silos of research and provide for alignment of investigators and trainees based on scientific interests and needs. This unique organizational model allows the Department of Pediatrics to adopt the novel approach to subspecialty research training described herein. In brief, each of the Centers will function as a training unit and scientific community for fellows. The scientific training and mentoring for individual fellows will be the responsibility of the selected training unit (Center) and its faculty, in addition to the traditional model of a named faculty mentor. Using this unique model, we were highly successful in the first 5 years of funding. We propose to renew this NRSA and plan to train a total of 8 MD or MD/PhD pediatric scientists over the next award period. A talented cadre of senior M.D. and Ph.D. scientists have enthusiastically agreed to serve as Program Faculty. Our unique training model, combined with the organizational commitment to build a first-rate research infrastructure, places Nationwide Children's Hospital in a favorable position to offer the highest caliber subspecialty research training program possible. PUBLIC HEALTH RELEVANCE: Recent advances in biomedical research have created an extraordinary opportunity for advancement in prevention and treatment of diseases of childhood by molecular approaches. A major obstacle is the lack of a well-trained workforce of pediatric physician scientists. This training grant is designed to aggressively train a cadre of outstanding pediatric scientists to meet this critical need for new talent.