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Conditional HSF1 Expression for Ischemic Cardioprotection

Conditional HSF1 Expression for Ischemic Cardioprotection
条件性 HSF1 表达对缺血性心脏保护作用
批准号：
7786189
负责人：
Ivor James Benjamin
金额：
$0.0万
依托单位：
VA SALT LAKE CITY HEALTHCARE SYSTEM
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-04-01 至 2013-03-31
来源：
https://reporter.nih.gov/project-details/7786189
关键词：
AccountingAcuteAcute myocardial infarctionAddressAdjuvant TherapyAffectAngiotensin-Converting Enzyme InhibitorsAnimal ModelApoptosisArrhythmiaArteriesBiochemicalBiologicalBlood PlateletsBlood flowCalciumCardiacCardiotonic AgentsCell DeathCessation of lifeChronicCigaretteClinicClinicalClinical ResearchClinical TrialsCoronary Artery BypassCoronary OcclusionsCytosolEndoplasmic ReticulumEpidemicEtiologyEventFree Radical ScavengersFree RadicalsFunctional disorderGene ExpressionGeneral PopulationGenesGoalsHSF1HealthHeartHeart DiseasesHeart TransplantationHeart failureHeat shock proteinsHeat-Shock ResponseHigh PrevalenceHomeostasisInflammationInheritedInjuryInterventionIschemiaKnowledgeLaboratoriesLeftLeft Ventricular DysfunctionLeft Ventricular Ejection FractionLeft Ventricular RemodelingMeasuresMediatingMedicalMembrane LipidsMitochondriaModelingMolecularMolecular ChaperonesMorbidity - disease rateMultigene FamilyMusMyocardialMyocardial InfarctionMyocardial IschemiaMyocardial dysfunctionNecrosisObesityOperative Surgical ProceduresOrganOrganellesOrganismOutcomeOutcome MeasureOxygen ConsumptionPathway interactionsPatientsPermeabilityPopulationPreventionProcessProductionProtein BiosynthesisProtein OverexpressionProteinsRandomizedReactive Oxygen SpeciesRecoveryRecurrenceRegulatory PathwayRepressionResearchResearch ProposalsRespirationSample SizeSodiumStimulusStressStrokeSyndromeTestingTherapeuticTherapeutic InterventionTimeTissue-Specific Gene ExpressionTissuesToxic effectTrans-ActivatorsTransgenic MiceTransgenic OrganismsTreatment EfficacyUnited StatesUp-RegulationVentricularVentricular RemodelingVeteransWomanbiological adaptation to stressclinically relevantcostdesigndisorder preventionefficacy testingheart metabolismheat shock transcription factorheat-shock factor 1high riskimprovedin vivointernal controlmembermenmitochondrial dysfunctionmortalitymouse modelnitrosative stressnovelnovel strategiespercutaneous coronary interventionpreclinical studypreventprogramsprotein aggregationprotein expressionprotein misfoldingpublic health relevanceresponserestorationsexstress proteinsudden cardiac deaththrombolysis

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Advancing Student Potential for Inclusion with Research Experiences (ASPIRE)
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    10678356
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  • 资助金额：
    $16.55万
  • 财政年份：
    2023
  • 负责人：
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    MEDICAL COLLEGE OF WISCONSIN
Training in Signature Transdisciplinary Cardiovascular Sciences
  • 批准号：
    10198992
  • 项目类别：
  • 资助金额：
    $40.76万
  • 财政年份：
    2017
  • 负责人：
    Ivor James Benjamin
  • 依托单位：
    MEDICAL COLLEGE OF WISCONSIN
Training in Signature Transdisciplinary Cardiovascular Sciences
  • 批准号：
    10628014
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  • 资助金额：
    $54.22万
  • 财政年份：
    2017
  • 负责人：
    Ivor James Benjamin
  • 依托单位：
    MEDICAL COLLEGE OF WISCONSIN
Training in Signature Transdisciplinary Cardiovascular Sciences
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    9209572
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    $13.56万
  • 财政年份：
    2017
  • 负责人：
    Ivor James Benjamin
  • 依托单位：
    MEDICAL COLLEGE OF WISCONSIN
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