Training Program in Neural Microcircuits

描述（由申请人提供）：项目摘要本提案旨在为神经微生物学的博士前和博士后培训计划提供资金。该计划的总体目标是培养一批优秀的研究人员，他们将：1）深入了解神经微生物学在广泛的神经系统功能中的作用原理; 2）在现代实验方法中进行广泛的研究培训，以分析神经微生物学。我们的课程为学员进行当代神经科学研究做好准备，这些研究弥合了突触，单个神经元，神经微生物学和行为之间的理解差距。该计划通过高级神经微生物学研究生课程，月刊俱乐部和神经微生物学研讨会的年度论文集来加强基本的博士前和博士后培训。在我们的就职资助期间，我们建立了一个充满活力的培训计划，新技术，发现和想法在教师，博士后研究员和博士前学生之间自由交流，促进互动和合作。迄今为止，我们在实现雄心勃勃的培训目标方面取得的成功来自于优秀的申请人和与神经微生物学相关的广泛领域的互动计划教师的实力。加州大学洛杉矶分校拥有出色的研究环境和一流的设施，24名教师拥有高度活跃的研究项目，最先进的实验室得到了大量的校外支持。提供援助的核心设施范围广泛，如分子生物学，包括病毒和转基因小鼠的制造以及先进的光学技术。该培训计划提供了独特的神经微生物学研究培训，这对于了解CNS的功能和行为以及开发治疗CNS病理变化的治疗策略至关重要。

DESCRIPTION (provided by applicant): Project Summary This proposal aims to renew funding for a pre- and post-doctoral training program in NEURAL MICROCIRCUITS. The overall goal of this program is to train a cadre of outstanding researchers who will have: 1) an in-depth understanding of the principles that underlie the function of NEURAL MICROCIRCUITS in a broad range of nervous system function, and; 2) extensive research training in modern experimental approaches to analyzing NEURAL MICROCIRCUITS. Our program prepares trainees to conduct contemporary neuroscience research that bridges the gaps in understanding between synapses, single neurons, NEURAL MICROCIRCUITS and behavior. The program enhances basic pre- and postdoctoral training with an advanced NEURAL MICROCIRCUITS graduate course, a monthly journal club, and an annual DYNAMICS OF NEURAL MICROCIRCUITS symposium. In our inaugural funding period we have established a vigorous training program where new techniques, findings, and ideas are freely exchanged among the faculty, postdoctoral fellows and predoctoral students that fosters interaction and collaboration. Our success to date in achieving our ambitious training goals results from an outstanding pool of applicants and the strength of the interactive program faculty in a broad range of areas relevant to NEURAL MICROCIRCUITS. An outstanding research environment and excellent facilities are available at UCLA, with 24 faculty with highly active research programs with state of the art laboratories funded by significant extramural support. A broad range of core facilities are available that offer assistance, such as in molecular biology including in the making of viruses and of transgenic mice and advanced optics. This training program provides unique research training in NEURAL MICROCIRCUITS, which is fundamental for an understanding of the function and behavior of the CNS and for the development of therapeutic strategies for the treatment of pathological changes in the CNS.