NIDCR DIR Production Facilities

认识到创新细胞疗法的必要性，NIDCR的领导在为建立跨NIH骨髓基质细胞移植中心获得支持和筹集资金方面发挥了重要作用。该中心源于一项提案，该提案是由一些研究所所长选择的，他们呼吁提出建议，以刺激新的NIH临床中心的新活动。该中心由NIDCR、NCI、NIAID、NINDS、NIAMS、NIBIB和CC于2008年10月1日成立。该中心的任务是建立临床级别的人骨髓基质细胞的制备程序，已发现这些细胞可以改善由于其对当地干细胞/祖细胞的营养作用而造成的一些损伤和条件。该中心的资金用于在输血医学部的细胞处理实验室内建立基础设施，以便在体外扩增细胞并保持其生物活性。在过去的11个月里，该中心取得了很大的进展。

Recognizing the need for innovative cell therapies, NIDCR leadership was instrumental in gaining support and raising funding for the establishment of a trans-NIH Bone Marrow Stromal Cell Transplantation Center. This Center arose from a proposal that was selected by a number of Institute Directors who issued a call for proposals that stimulate new activity in the new NIH Clinical Center. The Center was established on October 1st, 2008 by NIDCR, NCI, NIAID, NINDS, NIAMS, NIBIB and the CC. The mission of the Center is to establish the procedures for preparation of clinical grade human bone marrow stromal cells, which have been found to ameliorate a number injuries and conditions due to their trophic effect on local stem/progenitor cells. The Centers funding is for building of the infrastructure within the Cell Processing Laboratory in the Department of Transfusion Medicine to ex vivo expand the cells and still retain their biological activity. The Center has made a great deal of progress during the past 11 months.