Developing Infrastructure for Patient-Centered Outcomes Research at Denver Health

描述（由申请人提供）：我们建议在一个综合安全网卫生系统中建立一个卫生系统研究中心，其前提是安全网可以提供有关整个医疗保健系统可以学习的效率的经验教训。该中心的主题将是在安全网特有的资源限制的背景下为处境不利者设计系统，从而强调减少服务不足者的健康差距和比较提供系统的设计。我们将与一个学术研究单位和一个应用医疗研究组织合作，开发一个研究基础设施，并建立合作关系，以维持有意义的以患者为中心的成果研究，直到未来。基础设施的发展包括通过高度结构化的教学和导师计划建立我们新兴研究人员的方法技能，以及跨机构数据集成结构的发展，该结构将开始将我们与更大的研究网络连接起来。我们将通过描述丹佛抑郁症的地理位置来演示数据集成结构的功能。我们将在三个相关项目中评估体重管理、高危患者哮喘护理以及双重避孕和STD/HIV预防的新型干预措施的有效性。

DESCRIPTION (provided by applicant): We propose a Center for Health Systems Research at an integrated safety net health system, predicated on the view that the safety net can provide lessons about efficiency that the entire healthcare system can learn from. The Center's theme will be system design for the disadvantaged in the context of the resource constraints that are unique to the safety net, thus emphasizing both reduction of health disparities in the underserved and comparison of delivery system designs. We will partner with an academic research unit and an applied healthcare research organization to develop a research infrastructure and to create collaborations that will sustain meaningful patient-centered outcomes research well into the future. Infrastructure development includes building the methodological skills of our emerging investigators through a highly structured teaching and mentorship program, and development of a cross-institution data integration structure that will begin to connect us with much larger research networks. We will demonstrate functionality of the data integration structure with a description of the geography of depression in Denver. We will assess the effectiveness of novel interventions for weight management, for asthma care in high risk patients, and for dual contraception and STD/HIV prevention in three related projects.