Developing Infrastructure for Patient-Centered Outcomes Research at Denver Health

描述(由申请人提供)：我们建议建立一个卫生系统研究中心，以建立一个综合的安全网卫生系统，其基础是安全网可以提供有关效率的课程，整个卫生保健系统可以借鉴。该中心的主题将是在安全网特有的资源限制的背景下为弱势群体设计系统，从而既强调减少服务不足者的健康差距，又强调比较提供系统的设计。我们将与一个学术研究单位和一个应用医疗研究组织合作，开发一个研究基础设施，并建立合作，在未来很长一段时间内保持以患者为中心的有意义的研究成果。基础设施发展包括通过高度结构化的教学和指导计划为我们的新兴研究人员培养方法技能，以及开发跨机构的数据集成结构，该结构将开始将我们与更大的研究网络连接起来。我们将通过描述丹佛市抑郁症的地理位置来演示数据集成结构的功能。我们将评估体重控制、高危患者哮喘护理以及三个相关项目中双重避孕和性病/艾滋病毒预防的新干预措施的有效性。

DESCRIPTION (provided by applicant): We propose a Center for Health Systems Research at an integrated safety net health system, predicated on the view that the safety net can provide lessons about efficiency that the entire healthcare system can learn from. The Center's theme will be system design for the disadvantaged in the context of the resource constraints that are unique to the safety net, thus emphasizing both reduction of health disparities in the underserved and comparison of delivery system designs. We will partner with an academic research unit and an applied healthcare research organization to develop a research infrastructure and to create collaborations that will sustain meaningful patient-centered outcomes research well into the future. Infrastructure development includes building the methodological skills of our emerging investigators through a highly structured teaching and mentorship program, and development of a cross-institution data integration structure that will begin to connect us with much larger research networks. We will demonstrate functionality of the data integration structure with a description of the geography of depression in Denver. We will assess the effectiveness of novel interventions for weight management, for asthma care in high risk patients, and for dual contraception and STD/HIV prevention in three related projects.