2015 Epigenetics Gordon Research Seminar

 描述(由申请人提供)：表观遗传学戈登研究会议(GRC)是一个非常受欢迎的两年一次的会议，成立于一个快速增长和深入调查的领域的开始。在这次会议上提出的科学集中在基因组以稳定的、可遗传的方式对环境变化做出反应的无数方式上。在这次会议上观察和报告的现象背后的机制，直到现在才得到表面上的理解，定义了现在被接受的“表观遗传过程”。表观遗传学GRC一直是产生这种范式转变的大熔炉，因为它的出席人数有限，加上它新奇地坚持要广泛代表各种有机体的研究。正是这种有机体、系统和看似完全不同的现象的不同寻常的组合，使这次会议在推动该领域向前发展方面取得了特别的成果。长期存在的会议的一个固有问题是，随着时间的推移，与会者变得不那么多样化，变得更加孤立，无论其制度和科学如何多样化。出于这个原因，我们正在申请NIH基金，以支持学生和博士后参加为期两天的戈登研究研讨会(GRS)，该研讨会将在2015年表观遗传学GRC之前举行。GRS将由目前从事表观遗传学研究的研究生和博士后组织、主持和主要运行和参加。预计大多数GRS参与者将参加接下来的GRC，我们将强烈鼓励所有申请者参加。表观遗传学GRS的目标有几个：1)随着该领域的不断扩大，吸引并保持更多样化的年轻科学家群体；2)允许这些年轻科学家在一个不那么吓人的环境中向他们的同行展示他们的研究，并为他们更直接地参与随后的会议做好准备；3)为互动提供一个社会环境，随着他们的研究生涯的进步，这种互动将自然发展为专业的同行网络；以及4)提供一个研讨会，说明如何成功地发展以研究为导向的职业目标。GRS计划将与表观遗传学GRC历史上对系统/有机体表现的多样性的坚持相匹配，这也将使与会者接触到这次会议提供的各种想法、观点和技术--以及他们自己同行提供的暴露。通过有针对性的广告，一群高度多样化的年轻科学家将包括讨论领导者、演讲者和听众，这既将增强随后的GRC的多样性，也将增加这一令人兴奋的领域未来研究人员的多样性。表观遗传学GRC一直是一个高度活跃的会议，拟议的GRS将通过招募和激励新一代表观遗传学家来帮助保持这种活力。

 DESCRIPTION (provided by applicant): The Gordon Research Conference (GRC) on Epigenetics is a highly popular biennial conference that was established at the beginning of a rapidly growing and intensely investigated field. The science presented at this conference has focused on the myriad of ways in which genome responds, in a stable a heritable manner, to environmental changes. The mechanisms behind the phenomena observed and reported at this meeting, only now becoming superficially understood, define what are now embraced as "epigenetic processes". The Epigenetics GRC has been a cauldron for generating such paradigm shifts because of its restricted attendance coupled with its novel insistence that studies in a variety of organisms be broadly represented. It is this unusual mix of organisms, systems, and seemingly disparate phenomena that have made this conference particularly fruitful in propelling the field forward. An inherent problem in long-standing conferences, regardless of their diversity of systems and science, is the tendency for the participants to become less diverse and more insular over time. For this reason we are applying for NIH funds to support student and post-doc attendance at a two day Gordon Research Seminar (GRS) that will precede the 2015 Epigenetics GRC. The GRS will be organized, chaired, and largely run and attended by graduate students and post-docs who are currently engaged in epigenetics research. The majority of GRS participants are expected to attend the following GRC, and all applicants will be strongly encouraged to do so. The goals of the Epigenetics GRS are several: 1) to attract and maintain a more diverse group of young scientists into the field as it continues to expand; 2) to allow these young scientists to present their research to their peers in a less-intimidating environment and "prime" them for more direct participation in the subsequent conference; 3) to provide a social environment for interactions that will naturally develop into professional peer networks as they progress in their research careers; and 4) provide a workshop on how the successful development of research-oriented career goals can be achieved. The GRS program will match the Epigenetics GRC's historical insistence on diversity in system/organism representation, which will also provide the participants with the exposure to the variety of ideas, perspectives, and techniques that this conference provides-with the exposure provided by their own peers. Though targeted advertisements, a highly diverse group of young scientists will comprise the discussion leaders, speakers, and audience, which will both enhance the diversity of the subsequent GRC, and also increase the future diversity of researchers in this exciting field. The Epigenetics GRC has always been a highly dynamic conference, and the proposed GRS will help maintain that dynamism by recruiting and energizing a new generation of epigeneticists.