HMORN UCSF Center for Diabetes Translational Research

在美国，糖尿病是一个重大的健康和成本负担。预防和治疗2型糖尿病的证据基础是所有慢性病中最可靠的；然而，糖尿病的整体护理质量仍然不是最好的，到目前为止，预防糖尿病的计划相对较少受到关注。迫切需要能够有效地将高质量、循证的糖尿病预防和治疗转化为广泛实践的计划。针对这一需求，凯撒永久北加州研究部、健康伙伴研究基金会、哈佛朝圣者和加州大学旧金山分校的糖尿病研究人员提议创建糖尿病翻译研究中心(CDTR)，该中心将积极促进和支持HMO研究网络(HMORN)和加利福尼亚州附属医疗保健提供系统中的糖尿病翻译研究。拟议的HMORN-UCSF CDTR将通过发展一个由成熟的研究人员组成的多学科网络来实现其目标，该网络具有在糖尿病转化研究中接受联邦和基金会资助的强大历史。CDTR将围绕医疗保健差异、糖尿病和肥胖症预防以及利用健康信息技术改善糖尿病护理领域的三个翻译研究核心进行构建。拟议的CDTR调查员在成人和儿童以及妊娠期糖尿病(GDM)孕妇的T2 DM护理和预防方面拥有丰富的翻译研究经验。这些研究人员与护理交付系统有着密切的关系，从大型综合交付系统到安全网提供者网络，这些系统可以作为将有效干预措施转化为现实世界临床环境的重要合作伙伴。

Diabetes mellitus is a significant health and cost burden in the United States. The evidence base for the prevention and care of T2DM is one of the most well-established of any chronic illness; however, the overall quality of care for diabetes remains sub-optimal, and to date relatively little attention has been paid to programs for preventing diabetes. Programs which can effectively translate high-quality, evidence-based diabetes prevention and treatment into widespread practice are desperately needed. In response to this need, diabetes researchers at the Kaiser Permanente Northern California Division of Research, HealthPartners Research Foundation, Harvard Pilgrim, and the University of California San Francisco, propose to create a Center for Diabetes Translational Research (CDTR) that will actively foster and support translational research in diabetes within health care delivery systems affiliated with the HMO Research Network (HMORN) and the State of California. The proposed HMORN-UCSF CDTR will achieve its aims by developing a multi-disciplinary network of well-established investigators with a strong history of receiving both federal and foundation funding in diabetes translational research. This CDTR will be structured around three Translational Research Cores in the areas of health care disparities, diabetes and obesity prevention, and the use of health information technology to improve diabetes care. The proposed CDTR investigators have significant experience in translational research in T2DM care and prevention in both adults and children, as well as in pregnant women with gestational diabetes (GDM). These investigators have strong relationships with care delivery systems, ranging from large integrated delivery systems to networks of safety net providers, that can serve as important partners for translating effective interventions into real-world clinical settings.