Intestinal Stem Cell Consortium Coordinating Center

描述（由申请人提供）：肠道干细胞联盟协调中心（ISCC-CC）的总体目标是通过开发，共享和组织科学资源，包括生物材料，数据集，试剂，方法，协议，专业知识和信息，加速肠道干细胞研究。这项拨款提案的目标是继续维持和加强在City of Hope的ISCC再5年，与NIH选择的6-9个不同研究项目的研究人员合作，进行基础科学和翻译肠道干细胞（ISC）研究。该项目的具体目标是：1）促进ISCC必要的行政支持; 2）在ISCC内部和整个研究界提供信息管理和数据共享; 3）以高度成本效益和有效的方式协调共享资源的获取，广告和分配;以及4）通过提供ISCC-CC专业知识来推进ISCC的科学。COH的ISCC-CC完全准备好继续执行所有必要的任务，以最高质量的方式支持和加强ISCC。我们将利用我们在ISCC前5年的丰富经验，提供必要的行政管理，生物医学信息学，科学研究设计，分析和生物材料的分布，以促进ISCC进行的关键研究的各个方面。

DESCRIPTION (provided by applicant): The overall objective of the Intestinal Stem Cell Consortium Coordinating Center (ISCC-CC) is to accelerate intestinal stem cell research through the development, sharing, and organization of scientific resources, including biomaterials, datasets, reagents, methods, protocols, expertise, and information. The goal of this grant proposal is to continue to maintain and enhance the ISCC at City of Hope for another 5 years, working with investigators from 6-9 different research projects chosen by NIH to conduct fundamental basic science and translational Intestinal Stem Cell (ISC) research. The specific aims of this project are: 1) To facilitate the necessary administrative support of the ISCC; 2) To provide information management and data sharing within the ISCC, and across the research community; 3) To coordinate the acquisition, advertisement, and distribution of shared resources in a highly cost efficient, effective manner; and 4) To advance the science of the ISCC by providing ISCC-CC expertise. The ISCC-CC at COH is fully poised to continue conducting all tasks required to support and enhance the ISCC in the highest quality manner. We will draw upon our substantial experience with the ISCC over the first 5 years, to provide the necessary administrative, biomedical informatics, scientific study design, analysis, and distribution of biomaterials to facilitate all aspects of the critical research to be conducted by he ISCC.