2/2 The GUIDE Cancer Research Training Project

项目摘要/摘要(总体)： 来自美国服务不足的少数族裔社区的个人经历了糟糕的结果 大多数癌症是由于在获得高质量的医疗保健、社会文化和医疗服务方面的不平等 环境决定因素，在某些情况下还包括行为和生物因素。癌症中的不平等现象 结果植根于广泛的结构性、社会文化和与政策相关的决定因素， 在美国各地都在运作，但当地因素可能会永久存在并影响 不同的癌症结果。在某种程度上，少数民族中的高癌症死亡率 人口部分是一系列广泛的地方问题的全国性表现。一个有希望的人 解决癌症差异的战略是促进研究，以了解癌症的局部模式 死亡率和差异的根本原因，并测试根据这些发现得出的干预措施 考虑到当地社区的需求。这一解决癌症差异的范例具有 成功受雇于伊利诺伊大学的一大批癌症研究人员 癌症中心(UICC)已有十多年的历史，并构成了UICC愿景的基础--成为一名“长椅-- 到社区“NCI指定的癌症中心。州长州立大学(GSU)已投资 在基础科学和卫生科学基础设施方面大幅增加招聘教师的努力 对研究感兴趣的成员，并显著增强了研究支持服务 过去的几年里。因此，格拉斯哥州立大学定位于解决他们的癌症差距日益扩大的问题 社区。这项提议的总体目标是开发更多的基础设施，这些基础设施将在 伙伴关系机构的优势，以增强其开展癌症健康的能力 由当地数据驱动并由当地癌症相关需求提供信息的不平等研究 社区。

PROJECT SUMMARY/ABSTRACT (OVERALL): Individuals from underserved minority communities in the U.S. experience poor outcomes for the majority of cancers as a result of inequities in access to high quality healthcare, socio-cultural and environmental determinants, and in some cases behavioral and biologic factors. Inequities in cancer outcomes are rooted in a wide range of structural, socio-cultural, and policy-related determinants that are operative throughout the U.S., but local factors can perpetuate and influence the magnitude of disparate cancer outcomes. To some extent, high cancer mortality among racial and ethnic minority segments of the population is a national manifestation of a wide range of local problems. A promising strategy to address cancer disparities is to foster research to understand local patterns of cancer mortality and root causes of disparities, and to test interventions informed by those findings that account for the needs of the local community. This paradigm for addressing cancer disparities has been successfully employed by a large cadre of cancer researchers at the University of Illinois Cancer Center (UICC) for more than a decade and forms the basis of the UICC vision to be a “bench- to-community” NCI-designated cancer center. Governors State University (GSU) has invested substantially in basic science and health science infrastructure, increased efforts to recruit faculty members with an interest in research, and significantly enhanced research support services over the past several years. As a result, GSU is positioned to address growing cancer disparities in their community. The overall goal of this proposal is to develop additional infrastructure that will build on the strengths of the partnering institutions in order to enhance their capacity to conduct cancer health inequities research that is driven by local data and informed by the cancer-related needs of local communities.