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Borrelia miyamotoi: mechanisms of tick colonization and transmission

Borrelia miyamotoi: mechanisms of tick colonization and transmission
宫本伯氏疏螺旋体:蜱的定植和传播机制
批准号:
9196769
负责人:
Brian Stevenson
金额:
$23.95万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-07-01 至 2018-06-30

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中文摘要
翻译
摘要 人类感染螺旋体宫本疏螺旋体是美国新发现的公共卫生威胁, 世界上的其他地方。宫本疏螺旋体感染可能需要住院治疗,症状包括 高烧,关节和肌肉疼痛,脑膜脑炎。宫本杆菌通过被感染的蚊子叮咬传播。 硬蜱属(Ixodes Spp)扁虱,但几乎不知道细菌如何或在哪里定植其载体,或者 传播的动力学。这项建议汇集了一个由疏螺旋体和滴虫研究人员组成的专家团队,他们 将进行一系列协同研究,将极大地扩大对宫本杆菌传播的了解 和感染机制。
英文摘要
ABSTRACT Human infection by the spirochete Borrelia miyamotoi is a newly-recognized public health threat in the US and other parts of the world. Borrelia miyamotoi infection may require hospitalization, with symptoms that include high fever, joint and muscle pain, and meningoencephalitis. B. miyamotoi is spread by the bites of infected Ixodes spp. ticks, but almost nothing is known about how or where the bacterium colonizes its vector, or the dynamics of transmission. This proposal brings together an expert team of Borrelia and tick researchers, who will conduct a series of synergistic studies that will greatly expand understanding of B. miyamotoi transmission and infection mechanisms.
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  • 批准号:
    10597629
  • 项目类别:
  • 资助金额:
    $69.78万
  • 财政年份:
    2020
  • 负责人:
    Brian Stevenson
  • 依托单位:
海外基金