Fluorescence microscopy for proposed research in the parent grant

用于母基金拟议研究的荧光显微镜

• 批准号: 9330633
• 负责人: Maria Jasin
• 金额: $ 17.69万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-05-03 至 2021-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9330633
• 关键词: Address; Award; Cells; Chromosomes; DNA lesion; DNA replication fork; DNA strand break; Development; Fertility; Fluorescence Microscopy; Funding; Genetic Recombination; Genome; Genomics; Germ Cells; Grant; Healthcare; Human; Lead; Lesion; Malignant Neoplasms; Malignant neoplasm of ovary; Meiotic Recombination; Mitotic Recombination; Mus; Research; Somatic Cell; fluorescence microscope; live cell imaging; malignant breast neoplasm; mutant; parent grant; repaired; segregation; tumor

Fluorescence microscopy is required for the research in the newly funded grant R35GM118175. This application is to allow the purchase a fluorescence microscope. The need for fluorescence microscopy is clear from our previous research funded by two R01 applications folded in the R35 award mechanism. More than half of the project description for R35GM118175 involves the analysis of mouse and cell mutants for proficiency in recombination: meiotic recombination, mitotic recombination (somatic cells), and replication fork protection, and live cell imaging will add a new dynamic.

新基金R35GM118175中的研究需要荧光显微镜。 这个应用程序是为了让购买荧光显微镜。对荧光的需求 从我们之前由两个R01应用程序资助的研究中可以清楚地看到显微镜是在 R35奖励机制。 R35GM118175的一半以上的项目描述涉及鼠标和 精通重组的细胞突变体：减数分裂重组、有丝分裂重组 (体细胞)、复制分叉保护和活细胞成像将增添新的活力。