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Fluorescence microscopy for proposed research in the parent grant

Fluorescence microscopy for proposed research in the parent grant
用于母基金拟议研究的荧光显微镜
批准号:
9330633
负责人:
Maria Jasin
金额:
$17.69万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-05-03 至 2021-04-30

项目摘要

项目成果

Maria Jasin的其他基金

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中文摘要
翻译
荧光显微镜需要在新资助的赠款R35GM118175的研究。 此应用程序是允许购买荧光显微镜。对荧光的需求 显微镜是明确的,从我们以前的研究资助的两个R01应用程序折叠在 R35奖励机制。 R35GM118175的项目描述中有一半以上涉及对小鼠和 重组能力的细胞突变体:减数分裂重组,有丝分裂重组 (体细胞),复制叉保护,活细胞成像将增加一个新的动态。
英文摘要
Fluorescence microscopy is required for the research in the newly funded grant R35GM118175. This application is to allow the purchase a fluorescence microscope. The need for fluorescence microscopy is clear from our previous research funded by two R01 applications folded in the R35 award mechanism. More than half of the project description for R35GM118175 involves the analysis of mouse and cell mutants for proficiency in recombination: meiotic recombination, mitotic recombination (somatic cells), and replication fork protection, and live cell imaging will add a new dynamic.
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会议论文
Germline mutagenesis at meiotic double-strand breaks
Homology-directed repair: BRCA2 and RAD51 paralogs
Homology-directed repair: BRCA2 and RAD51 paralogs
Homology-directed repair: BRCA2 and RAD51 paralogs
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