An Internet-Based Behavioral Intervention for Individuals Diagnosed with Melanoma

描述（由申请人提供）：诊断为黑色素瘤的个体有疾病复发和第二原发性黑色素瘤的风险，建议他们定期进行彻底的皮肤自我检查，并定期进行防晒行为。然而，以前的研究表明，大多数黑色素瘤患者没有足够定期地进行皮肤自我检查，并且当他们这样做时，他们没有对身体的所有区域进行彻底检查。许多患者也未能从事一个或多个防晒行为。这项研究的目的是开发和测试一种创新的行为干预措施，以促进黑色素瘤患者的皮肤监测和防晒行为。干预措施将通过互联网提供，而不是其他提供渠道，因为这是一种有效和潜在的低成本方式， 为患者量身定制的内容。该项目将分两个阶段进行。第1阶段侧重于干预措施的开发、可接受性和可用性测试以及改进。第二阶段是一项随机对照试验，比较了互动式定制网站与 日常护理，促进患者进行彻底的皮肤自我检查和防晒行为。该项目的主要目的是评估交互式定制网站与常规护理对彻底的皮肤自我检查和防晒行为的影响。该项目的第二个目的是确定干预措施影响的调解人，这将有助于从概念上理解干预措施为什么有效，并有助于制定更有效的干预措施。该项目的探索性目的是检查干预影响的调节者。这将确定对干预措施的影响特别敏感或抵抗的患者亚组，这将为未来的干预措施开发和目标确定提供信息。

DESCRIPTION (provided by applicant): Individuals diagnosed with melanoma are at risk for disease recurrence and second primary melanoma and it is recommended that they regularly perform thorough skin self-examination and routinely engage in sun protection behaviors. However, previous research indicates that the majority of melanoma patients do not perform skin self-examination on a sufficiently regular basis, and when they do so, they do not conduct a thorough inspection of all areas of the body. Many patients also fail to engage in one or more sun protection behaviors. The goal of the proposed research is to develop and test an innovative behavioral intervention to promote skin surveillance and sun protection behaviors among melanoma patients. The intervention will be delivered via the Internet as opposed to other delivery channels, as it is an efficient and potentially low cost way to deliver interactive, personally tailored content to patients. The project will be conducted in two phases. Phase 1 focuses on intervention development, acceptability and usability testing, and refinement. Phase 2 is a randomized controlled trial comparing the efficacy of an interactive tailored website versus usual care in promoting patients' engagement in thorough skin self-examination and sun protection behaviors. The primary aim of the project is to evaluate the impact of the interactive tailored website versus usual care on thorough skin self-examination and sun protection behaviors. The secondary aim of the project is to identify mediators of the impact of the intervention, which will facilitate a conceptual understanding of why the intervention worked and will also aid the development of more effective interventions. The exploratory aim of the project is to examine moderators of the impact of the intervention. This will identify patient subgroups that are particularly amenable or resistant to the effects of the intervention, which will inform future intervention development and targeting.