An Internet-Based Behavioral Intervention for Individuals Diagnosed with Melanoma

描述(申请人提供)：被诊断为黑色素瘤的人有疾病复发和第二原发黑色素瘤的风险，建议他们定期进行彻底的皮肤自我检查，并定期进行防晒行为。然而，此前的研究表明，大多数黑色素瘤患者没有足够定期地进行皮肤自我检查，而且当他们这样做时，他们也没有对身体的所有部位进行彻底检查。许多患者也没有进行一种或多种防晒行为。这项拟议研究的目标是开发和测试一种创新的行为干预措施，以促进黑色素瘤患者的皮肤监测和防晒行为。干预将通过互联网传递，而不是其他传递渠道，因为这是一种有效且潜在低成本的传递互动的方式， 亲自为患者量身定做内容。该项目将分两个阶段进行。第一阶段侧重于干预开发、可接受性和可用性测试，以及改进。第二阶段是一项随机对照试验，比较了互动定制网站和 在促进患者进行彻底的皮肤自我检查和防晒行为方面的日常护理。该项目的主要目的是评估互动定制网站与常规护理对彻底的皮肤自我检查和防晒行为的影响。该项目的次要目标是确定干预影响的调解人，这将有助于从概念上了解干预为什么奏效，也将有助于制定更有效的干预措施。该项目的探索性目标是检查干预的影响的主持人。这将确定对干预效果特别顺从或抵抗的患者亚群，这将为未来干预的发展和目标提供信息。

DESCRIPTION (provided by applicant): Individuals diagnosed with melanoma are at risk for disease recurrence and second primary melanoma and it is recommended that they regularly perform thorough skin self-examination and routinely engage in sun protection behaviors. However, previous research indicates that the majority of melanoma patients do not perform skin self-examination on a sufficiently regular basis, and when they do so, they do not conduct a thorough inspection of all areas of the body. Many patients also fail to engage in one or more sun protection behaviors. The goal of the proposed research is to develop and test an innovative behavioral intervention to promote skin surveillance and sun protection behaviors among melanoma patients. The intervention will be delivered via the Internet as opposed to other delivery channels, as it is an efficient and potentially low cost way to deliver interactive, personally tailored content to patients. The project will be conducted in two phases. Phase 1 focuses on intervention development, acceptability and usability testing, and refinement. Phase 2 is a randomized controlled trial comparing the efficacy of an interactive tailored website versus usual care in promoting patients' engagement in thorough skin self-examination and sun protection behaviors. The primary aim of the project is to evaluate the impact of the interactive tailored website versus usual care on thorough skin self-examination and sun protection behaviors. The secondary aim of the project is to identify mediators of the impact of the intervention, which will facilitate a conceptual understanding of why the intervention worked and will also aid the development of more effective interventions. The exploratory aim of the project is to examine moderators of the impact of the intervention. This will identify patient subgroups that are particularly amenable or resistant to the effects of the intervention, which will inform future intervention development and targeting.