Parathyroid hormone-related protein (PTHrP), common genetic variants in the PTHrP gene (PTHLH), and breast cancer risk and survival

在彼得·麦卡勒姆癌症中心、圣文森特医院和墨尔本大学的合作下，我们正在研究PTHrP的作用，PTHrP是癌症生长和扩散中不可或缺的一种多肽。最初被认为是促进癌症扩散的，最近的研究表明，它实际上可能具有保护作用。在一种新的方法中，我们将分析来自世界各地的新DNA数据库和患者数据。我们希望扩大对PTHrP的认识，并可能发现新的药物和治疗靶点。

In a partnership between Peter MacCallum Cancer Centre, St Vincent's Hospital, and The University of Melbourne, we are investigating the role of PTHrP, a peptide integral to the growth and spread of Cancer. Initially thought to facilitate cancer spread, recent studies suggest it may actually be protective. In a new approach, we will analyse new DNA databases and patient data from around the world. We hope to extend our understanding of PTHrP, and perhaps find novel drug and therapeutic targets.