Parathyroid hormone-related protein (PTHrP), common genetic variants in the PTHrP gene (PTHLH), and breast cancer risk and survival

甲状旁腺激素相关蛋白 (PTHrP)、PTHrP 基因 (PTHLH) 的常见遗传变异以及乳腺癌风险和生存

• 批准号: nhmrc : 1056369
• 负责人: Dr Adam Freeman
• 金额: $ 8.02万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/parathyroid-hormone-related-risk-survival/112548
• 关键词: Parathyroid; hormone; related; protein; PTHrP

In a partnership between Peter MacCallum Cancer Centre, St Vincent's Hospital, and The University of Melbourne, we are investigating the role of PTHrP, a peptide integral to the growth and spread of Cancer. Initially thought to facilitate cancer spread, recent studies suggest it may actually be protective. In a new approach, we will analyse new DNA databases and patient data from around the world. We hope to extend our understanding of PTHrP, and perhaps find novel drug and therapeutic targets.

在Peter MacCallum癌症中心，圣文森特医院和墨尔本大学之间的合作中，我们正在研究PTHrP的作用，PTHrP是一种与癌症生长和扩散不可或缺的肽。最初被认为是促进癌症扩散，最近的研究表明它实际上可能是保护性的。在一种新的方法中，我们将分析来自世界各地的新DNA数据库和患者数据。我们希望能扩展我们对PTHrP的理解，并可能找到新的药物和治疗靶点。