Parathyroid hormone-related protein (PTHrP), common genetic variants in the PTHrP gene (PTHLH), and breast cancer risk and survival

在Peter MacCallum癌症中心、圣文森特医院和墨尔本大学的合作中，我们正在研究PTHrP的作用，PTHrP是一种对癌症生长和扩散不可或缺的肽。最初人们认为它会促进癌症扩散，但最近的研究表明，它实际上可能具有保护作用。在一种新的方法中，我们将分析新的DNA数据库和来自世界各地的患者数据。我们希望扩展我们对PTHrP的理解，并可能找到新的药物和治疗靶点。

In a partnership between Peter MacCallum Cancer Centre, St Vincent's Hospital, and The University of Melbourne, we are investigating the role of PTHrP, a peptide integral to the growth and spread of Cancer. Initially thought to facilitate cancer spread, recent studies suggest it may actually be protective. In a new approach, we will analyse new DNA databases and patient data from around the world. We hope to extend our understanding of PTHrP, and perhaps find novel drug and therapeutic targets.