Engineering an Online STI Prevention Program

制定在线性传播感染预防计划

基本信息

批准号：
9105672
负责人：
LINDA M COLLINS
金额：
$ 62.35万
依托单位：
PENNSYLVANIA STATE UNIVERSITY, THE
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-07-06 至 2020-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9105672
关键词：
AIDS prevention Affect African American African American student Alcohol consumption Alcohols Attention Behavior Therapy Behavioral Biological Chlamydia trachomatis Diagnosis Effectiveness Engineering Ensure Event Female Generations Goals HIV Health Historically Black Colleges and Universities Incidence Individual Infection prevention Interdisciplinary Study Internet Intervention Laboratories Lead Life Link Measures Mediator of activation protein Modeling Multiple Partners Neisseria gonorrhoeae Outcome Population Population Heterogeneity Prevention Prevention program Preventive Intervention Privacy Public Health Randomized Research Research Personnel Risk Rural Sampling Schools Science Scientist Self-Administered Sex Behavior Sexually Transmitted Diseases Students Testing Time Universities Unsafe Sex Ursidae Family Work alcohol intervention base college community college condoms cost cost effective experience field study high risk improved innovation male novel strategies prevent reduced alcohol use research study secondary outcome sex sex risk sexual encounter sexual minority success theories therapy development transmission process university student young adult

项目摘要

DESCRIPTION (provided by applicant): The overall objective of the proposed research is to reduce the incidence of sexually transmitted infections (STIs) among college students. We propose to accomplish this by using the innovative, engineering-inspired multiphase optimization strategy (MOST) to develop a highly effective, appealing, economical, and readily scalable internet-delivered behavioral intervention targeting the intersection of alcohol use and sexual risk behavior. The rate of STIs on college campuses is alarming: one in four college students is diagnosed with an STI at least once during their college experience. Sexual activity when drinking alcohol is highly prevalent among college students. Alcohol use is known to contribute to the sexual risk behaviors that are most responsible for the transmission of STIs, namely unprotected sex, contact with numerous partners, and "hook- ups" (casual sexual encounters). Few interventions have been developed that explicitly target the intersection of alcohol use and sexual risk behaviors, and none have been optimized. In order to reduce the incidence of STI transmission among this and other high-risk groups, a new approach is needed. MOST is a comprehensive methodological framework that brings the power of engineering principles to bear on optimization of behavioral interventions. MOST enables researchers to experimentally test the individual components in an intervention to determine their effectiveness, indicating which components need to be revised and re-tested. Given the high rates of alcohol use and sex among college students, the college setting provides an ideal opportunity for intervening on alcohol use and sexual risk behaviors. The proposed study will include a diverse population of college students (˜ 50% African American) on 4 campuses: 2 Historically Black Colleges and Universities, 1 large public university, and 1 junior college. This will increase the generalizability of our findings. Our specific aims are to (1) develop and pilot test an initial set of online intervention components targeting the link between alcohol use and sexual risk behaviors, (2) use the MOST approach to build an optimized preventive intervention, and (3) evaluate the effectiveness of the newly optimized preventive intervention using a fully powered RCT. This work will result in a new, more potent behavioral intervention that will reduce the incidence of STIs among college students in the US, and will lay the groundwork for a new generation of highly effective STI prevention interventions aimed at other subpopulations at risk.

描述（由适用提供）：拟议研究的总体目标是减少大学生中性传播感染（STI）的发生率。我们建议通过使用创新的，工程启发的多相优化策略（大多数）来制定一种高效，有吸引力，经济且易于扩展的互联网行为干预措施，以针对酒精使用和性风险行为的交汇处。大学校园的性传播感染率令人震惊：四分之一的大学生在大学经历期间至少被诊断出患有一次性传播感染。饮酒时性活动在大学生中非常普遍。众所周知，饮酒是有助于最负责性传播感染传播的性风险行为，即无保护的性行为，与众多伴侣接触和“连接”（随意的性交）。很少开发出明确针对酒精使用和性风险行为交汇的干预措施，并且没有进行优化。为了减少该和其他高风险组之间的性传播感染传播的发生率，需要一种新的方法。大多数是一个综合的方法论框架，它带来了工程原则以优化行为干预措施的力量。大多数研究人员能够在干预措施中测试各个组件以确定其有效性，表明需要修改哪些组件并重新测试哪些组件。鉴于大学生的酒精使用率很高，大学环境为介入酒精使用和性风险行为提供了理想的机会。拟议的研究将包括4个校园的大学生（约50％的非洲裔美国人）的多样性人群：2个历史上的黑人学院和大学，1个大型公立大学和1个初中学院。这我们的具体目的是（1）开发和试点测试一组针对酒精使用与性风险行为之间联系的初始在线干预组件，（2）使用最优化的预防性干预措施，以及（3）评估新优化的预防性干预措施的有效性。这项工作将导致一种新的潜在行为干预措施，这将减少美国大学生之间的性传播感染的发生率，并为新一代的高效性STI预防干预措施奠定基础，该干预措施旨在旨在其他有风险的亚种群。