QMRA III - Quantitative Microbial Risk Assessment Interdisciplinary Instructional

描述（由申请人提供）：定量微生物风险评估（QMRA）是一个不断发展的多学科领域，包括一个针对微生物病原体暴露和传染病过程的QMRA正式过程。QMRA在人类健康风险测量方面比传统的流行病学方法具有更高的灵敏度，已成为水质和食品研究的广泛接受的框架。处于数学、生物学、工程学和政策的交汇点，风险评估是一种复杂但非常有用的方法，适用于各种疾病情况。风险评估促进了公共卫生、应急响应、环境控制措施、去污、工业卫生和医疗对策方面的决策科学。风险分析还必须包括风险沟通和风险认知，以便了解应采取哪些风险缓解决策。尽管QMRA方法很实用，但很少有生物或社会科学家在这一过程中接受过培训，或者有足够的统计和定量技能进行这种分析，并且缺乏建模技能的人几乎没有QMRA工具或模型。同样，很少有统计学家或建模者拥有必要的社会科学技能，以充分解决影响接触病原体的人类行为问题，或对真实的或感知的健康风险的反应。我们将提供QMRA培训，以加强与这些关键能力和知识差距相关的多学科研究，通过为期两周的强化短期课程，将：（1）提供识别和量化风险的培训;（2）提供风险感知和沟通的培训;（3）开发学习QMRA的工具和课程，并免费提供;以及（4）开发和发布具有全球和临床意义的新兴病原体的新风险分析。QMRA III建立在一个成功的为期一周的强化课程，该课程由推进微生物风险评估中心（CAMRA）从2006年到2011年每年进行。它对来自不同背景的学生进行实际操作培训，提高了参与者在工作中使用质量管理和报告评估的能力。QMRA III将为生物医学和行为科学家提供高度可信的定量微生物风险评估所需的培训和工具，支持有关新兴病原体和疾病预防的循证公共卫生政策。

DESCRIPTION (provided by applicant): Quantitative microbial risk assessment (QMRA) is a growing multidisciplinary field consisting of a formal process for .QMRA addressing exposures to microbial pathogens and infectious disease processes. QMRA provides greater sensitivity in human health risk measurement than conventional epidemiological approaches, and has become a widely accepted framework for the study of water quality and food. Lying at the confluence of mathematics, biology, engineering, and policy, risk assessment is a complex but highly useful approach applicable to a wide variety of disease scenarios. Risk assessment advances decision science in public health, emergency response, environmental control measures, decontamination, industrial hygiene, and medical countermeasures. Risk analyses must also include risk communication and risk perception in order to know which risk mitigation decisions to take. Despite the utility of the QMRA approach, few biological or social scientists are trained in this process or have sufficient statistical and quantitative skills for such analyse, and few QMRA tools or models are available to people lacking modeling skills. Similarly, few statisticians or modelers possess the necessary social science skills to adequately address issues of human behavior that affect exposure to pathogenic agents, or responses to real or perceived health risks. We will provide QMRA training to enhance multidisciplinary research associated with these key proficiency and knowledge gaps through a two week, intensive short course that will: (1) provide training in identifying and quantifying risk; (2) provide training inrisk perception and communication; (3) develop tools and lessons for learning QMRA and make them freely available; and (4) develop and publish novel risk analyses of emerging pathogens of global and clinical significance. QMRA III builds upon a successful week-long intensive course that was conducted annually by the Center for Advancing Microbial Risk Assessment (CAMRA) from 2006 to 2011. Its application of practical, hands-on training to students from diverse backgrounds enhanced participants' ability to use QMRA in their work. QMRA III will equip biomedical and behavioral scientists with training and tools necessary for highly credible quantitative microbial risk assessments, supporting evidence-based public health policies regarding emerging pathogens and disease prevention.