Alliance for Regenerative Rehabilitation Research & Training Collaborative Opportunities

摘要 优化组织再生和修复的再生修复方法的研究进展 有可能提高对一系列伤害和疾病的康复干预的效率。至 为了加速这一新兴领域的科学进步，并将学科障碍降至最低，AR3T已组装 在STEM领域进行最先进研究的多机构实验室网络 细胞生物学、生物标志物、组织可塑性和再生，以及再生医学疗法。这 网络将提供广泛的咨询服务，旨在丰富医学研究的能力 三个核心领域的康复研究社区：细胞治疗/组织工程， 机械传递方法、康复和机械敏感生物标记物(具体目标2a)。 外部研究人员和AR3T教职员工之间的合作项目将通过 一项积极的全国性营销活动，以突出AR3T核心提供的服务。为了进一步鼓励 利用我们的核心资源，我们将免费向外部调查人员提供服务，同时补偿非 关键人员花费时间咨询外部调查人员。AR3T内核模拟了高度成功的 匹兹堡大学临床和翻译科学研究所的模板，它拥有一条漫长的轨道 向广泛的研究社区提供类似服务的记录。 鼓励有兴趣从事再生康复研究的外部研究人员 参加实践经验和培训，我们设计了AR3T奖学金计划(专门针对 2B)。该计划将为调查人员提供短期访问和休假的机会 在AR3T实验室之一的经验，从一周到三个月不等。为了尽量减少 参与该计划的潜在障碍，AR3T将为学者提供津贴支持，以抵消 他们在东道国机构逗留期间的住房费用。此外，主办机构将获得补偿 访问学者所使用的人员、时间和研究用品。我们期待这一成功 拟议目标的完成将催生新的和有希望的合作调查(AS 由手稿和拨款申请证明)和一代科学家致力于 追求再生康复研究事业。

ABSTRACT The development of Regenerative Rehabilitation approaches to optimize tissue regeneration and repair has the potential to enhance the efficiency of rehabilitation interventions for a host of injuries and diseases. To accelerate scientific progress in this emerging field and to minimize disciplinary barriers, AR3T has assembled a multi-institutional network of laboratories that are conducting state-of-the-art research in the domains of stem cell biology, biomarkers, tissue plasticity and regeneration, and regenerative medicine therapeutics. This network will offer a broad range of consultative services intended to enrich the research capacity of the medical rehabilitation research community across three core areas: Cellular Therapeutics/Tissue Engineering, Mechanotransductive Methods, and Rehabilitation & Mechanosensitive Biomarkers (Specific Aim 2a). Collaborative projects between external investigators and AR3T faculty members will be incentivized through an aggressive national marketing campaign to highlight services offered by AR3T Cores. To further encourage utilization of our Core resources, we will offer services gratis to external investigators, while compensating non- key personnel for time spent consulting with external investigators. AR3T Cores model the highly successful template of the University of Pittsburgh Clinical and Translational Science Institute, which boasts a long track record of offering similar services to a broad research community. To encourage external investigators with interest in pursuing Regenerative Rehabilitation research to participate in hands-on experiences and training, we have designed the AR3T Scholars Program (Specific Aim 2b). This program will provide investigators with the opportunity for short-term visits and sabbatical experiences at one of the AR3T laboratories, ranging from one week to three months. In an attempt to minimize potential barriers to participation in this program, AR3T will provide Scholars with stipend support to offset housing costs during their stay at the host institution. In addition, the host institutions will receive compensation for personnel time and research supplies utilized by the visiting Scholar. We anticipate that successful completion of the proposed aims will catalyze novel and promising lines of collaborative investigations (as evidenced by manuscripts and grant submissions) and the expansion of a generation of scientists committed to pursing Regenerative Rehabilitation research careers.