Alliance for Regenerative Rehabilitation Research & Training Collaborative Opportunities

再生康复研究联盟

• 批准号: 9145755
• 负责人: MICHAEL L. BONINGER
• 金额: $ 13.31万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9145755
• 关键词: Area; Biological Markers; Bioreactors; Cell physiology; Clinical Sciences; Collaborations; Communities; Consult; Country; Data Analyses; Development; Disease; Exercise; Faculty; Financial compensation; Fostering; Generations; Goals; Grant; Housing; Human Resources; Individual; Injury; Institutes; Institution; Intervention; Investigation; Laboratories; Manuscripts; Marketing; Measures; Mechanics; Methods; Modality; Modeling; NCI Scholars Program; Natural regeneration; Protocols documentation; Regenerative Medicine; Rehabilitation Research; Rehabilitation therapy; Research; Research Design; Research Infrastructure; Research Personnel; Research Training; Resources; Scientist; Services; Stem cells; Stimulus; Technology; Therapeutic; Time; Tissue Engineering; Training; Translational Research; Universities; Visit; Work; base; career; cost; design; experience; inter-institutional; interest; member; novel; programs; protocol development; regenerative; sabbatical; specific biomarkers; stem cell biology; tissue biomarkers; tissue regeneration; tissue repair; visiting scholar

ABSTRACT The development of Regenerative Rehabilitation approaches to optimize tissue regeneration and repair has the potential to enhance the efficiency of rehabilitation interventions for a host of injuries and diseases. To accelerate scientific progress in this emerging field and to minimize disciplinary barriers, AR3T has assembled a multi-institutional network of laboratories that are conducting state-of-the-art research in the domains of stem cell biology, biomarkers, tissue plasticity and regeneration, and regenerative medicine therapeutics. This network will offer a broad range of consultative services intended to enrich the research capacity of the medical rehabilitation research community across three core areas: Cellular Therapeutics/Tissue Engineering, Mechanotransductive Methods, and Rehabilitation & Mechanosensitive Biomarkers (Specific Aim 2a). Collaborative projects between external investigators and AR3T faculty members will be incentivized through an aggressive national marketing campaign to highlight services offered by AR3T Cores. To further encourage utilization of our Core resources, we will offer services gratis to external investigators, while compensating non- key personnel for time spent consulting with external investigators. AR3T Cores model the highly successful template of the University of Pittsburgh Clinical and Translational Science Institute, which boasts a long track record of offering similar services to a broad research community. To encourage external investigators with interest in pursuing Regenerative Rehabilitation research to participate in hands-on experiences and training, we have designed the AR3T Scholars Program (Specific Aim 2b). This program will provide investigators with the opportunity for short-term visits and sabbatical experiences at one of the AR3T laboratories, ranging from one week to three months. In an attempt to minimize potential barriers to participation in this program, AR3T will provide Scholars with stipend support to offset housing costs during their stay at the host institution. In addition, the host institutions will receive compensation for personnel time and research supplies utilized by the visiting Scholar. We anticipate that successful completion of the proposed aims will catalyze novel and promising lines of collaborative investigations (as evidenced by manuscripts and grant submissions) and the expansion of a generation of scientists committed to pursing Regenerative Rehabilitation research careers.

摘要 再生康复方法的发展，以优化组织再生和修复 有可能提高对许多伤害和疾病的康复干预的效率。到 加速这一新兴领域的科学进步，并最大限度地减少学科障碍，AR3T已经聚集了 在科学、技术、工程和管理领域进行最先进研究的多机构实验室网络 细胞生物学、生物标志物、组织可塑性和再生，以及再生医学治疗。这 网络将提供广泛的咨询服务，旨在丰富医学研究能力。 康复研究社区跨越三个核心领域：细胞治疗/组织工程， 机械转导方法，康复和机械敏感生物标志物（具体目标2a）。 外部研究人员和AR3T教职员工之间的合作项目将通过以下方式得到激励： 积极的全国营销活动，以突出AR3T核心提供的服务。进一步鼓励 利用我们的核心资源，我们将免费为外部调查人员提供服务，同时补偿非 关键人员与外部调查人员进行咨询所花费的时间。AR3T核心模拟了 匹兹堡大学临床和转化科学研究所的模板，该研究所拥有一个长期的跟踪 为广泛的研究社区提供类似服务的记录。 鼓励有兴趣从事再生康复研究的外部研究人员， 参加实践经验和培训，我们设计了AR 3 T学者计划（特定目标 2b）。该计划将为研究者提供短期访问和休假的机会 在AR3T实验室之一的经验，从一周到三个月不等。为了尽量减少 参与该计划的潜在障碍，AR3T将为学者提供助学金支持，以抵消 他们在东道机构逗留期间的住房费用。此外，主办机构将获得补偿 访问学者使用的人员时间和研究用品。我们预计， 完成拟议的目标将促进新的和有前途的合作研究（如 手稿和赠款提交证明）和一代科学家致力于扩大 从事再生康复研究事业