Take Active Breaks from Sitting (TABS): Reducing Sedentary Time in Obese Older Adults

描述(申请人提供)：65岁以上的成年人中有三分之一肥胖。虽然之前的研究重点是促进体育锻炼，以减轻肥胖和老龄化带来的健康负担，但在老年人和肥胖者中，体育锻炼水平仍然很低。一种解释可能是，对于肥胖的老年人来说，进行中等强度的体力活动的障碍太高(例如，身体机能低下、疼痛、缺乏动力)。同时 时间上，肥胖的老年人每天坐着的时间超过10个小时，比其他任何年龄段的人都多。新出现的研究表明，久坐对健康有不利影响，与满足体力活动指南无关。对于肥胖的老年人来说，克服减少久坐时间的障碍可能是一种更可行的健康促进行为。因此，我们的目标是探索一种新的方法来改善肥胖老年人的健康，他们患有或发展慢性健康状况的风险很高，重点是减少久坐时间。在我们的前期工作中，我们制定了程序和干预材料，在一项小型单臂研究中显示了久坐时间的减少，并确立了我们方法的初步可行性。目前的随机试点研究将正式评估我们创新的基于电话的干预措施的可行性、可接受性和影响，该干预措施旨在使用更长时间和更密集的干预措施，减少久坐肥胖老年人的坐姿时间，增加光强度体力活动。我们将把干预措施与接受健康老龄化教育计划(每组30名参与者)的注意力匹配的对照组进行比较。研究结果将在12周时进行测量，包括久坐时间和坐立转换(来自活动PAL倾斜仪)、光强度体力活动(来自加速计)和心血管危险因素生物标记物。如果干预是可行的，并显示出减少久坐时间的希望，我们将计划未来的随机疗效试验。除了减少久坐不动的行为外，这项研究的长期目标是创造一种有效的干预措施，将 让研究人员更好地了解减少老年人和肥胖者久坐对健康的潜在影响。到目前为止，还没有这种经过经验验证的干预措施。因此，这项形成性研究将对这一研究领域做出独特而有意义的贡献。这项工作与NIA的战略重点很好地结合在一起，即研究在慢性病患者中促进健康和积极老龄化的方法。

DESCRIPTION (provided by applicant): One-third of adults over 65 are obese. While previous studies have focused on promoting physical activity to reduce the health burdens of obesity and aging, physical activity levels have remained low among older adults and those with obesity. One explanation may be that the barriers to engaging in moderate intensity physical activity are too high for obese older adults (e.g. low physical function, pain, lack of motivation). At the same time, obese older adults spend over 10 hours per day sitting, more than any other age group. Emerging research now shows that sitting time has adverse health impacts, independent of meeting physical activity guidelines. Overcoming the barriers to reducing sedentary time may be a more feasible health-promoting behavior for obese older adults. Thus, we aim to explore a new approach to improving the health of obese older adults, who are at high risk for having or developing chronic health conditions, by focusing on reducing sedentary time. In our preliminary work, we developed procedures and intervention materials, showed reductions in sedentary time in a small one arm study, and established preliminary feasibility of our approach. The current randomized pilot study will formally assess the feasibility, acceptability, and impact of our innovative phone-based intervention designed to decrease sitting time and increase light intensity physical activity among sedentary obese older adults using a longer and more intensive intervention. We will compare the intervention to an attention-matched comparison group that receives a healthy aging education program (30 participants per group). Study outcomes, including sedentary time and sit-to-stand transitions (from activPAL inclinometers), light intensity physical activity (from accelerometers), and cardiovascular risk factor biomarkers will be measured at 12 weeks. If the intervention is feasible and shows promise for reducing sedentary time, we will plan a future randomized efficacy trial. In addition to reducing sedentary behavior, the long-term objective of this research is to create an effective intervention that will allow researchers to better understand the potential health impacts of reducing sitting among older and obese adults. To date, no such empirically validated interventions exist. As such, this formative research stands to make a unique and meaningful contribution to this field of research. This work is well-aligned with NIA's strategic focus on examining ways to promote healthy and active aging among those with chronic conditions.