Take Active Breaks from Sitting (TABS): Reducing Sedentary Time in Obese Older Adults

描述（由申请人提供）：65岁以上的成年人中有三分之一肥胖。虽然以前的研究集中在促进体育活动以减少肥胖和衰老的健康负担，但老年人和肥胖者的体育活动水平仍然很低。一种解释可能是，对于肥胖的老年人来说，从事中等强度体力活动的障碍太高（例如，身体功能低下，疼痛，缺乏动力）。在同一 肥胖的老年人每天坐着的时间超过10个小时，比其他任何年龄组都多。新兴的研究现在表明，坐着的时间对健康有不利的影响，与满足身体活动指南无关。克服减少久坐时间的障碍可能是肥胖老年人更可行的健康促进行为。因此，我们的目标是探索一种新的方法来改善肥胖老年人的健康，他们是高风险的有或发展慢性健康状况，通过专注于减少久坐的时间。在我们的初步工作中，我们开发了程序和干预材料，在一项小型单臂研究中显示了久坐时间的减少，并建立了我们方法的初步可行性。目前的随机试点研究将正式评估我们创新的基于电话的干预的可行性，可接受性和影响，旨在减少久坐不动的肥胖老年人使用更长时间和更密集的干预减少坐着的时间和增加轻强度的身体活动。我们将把干预措施与接受健康老龄化教育计划的注意力匹配对照组（每组30名参与者）进行比较。将在第12周测量研究结局，包括久坐时间和坐立转换（来自activPAL倾斜仪）、轻强度体力活动（来自加速度计）和心血管风险因素生物标志物。如果干预是可行的，并显示出减少久坐时间的希望，我们将计划未来的随机疗效试验。除了减少久坐行为，这项研究的长期目标是创造一种有效的干预措施， 使研究人员能够更好地了解减少老年人和肥胖成年人坐着的潜在健康影响。到目前为止，还没有这种经过经验验证的干预措施。因此，这种形成性研究将为这一研究领域做出独特而有意义的贡献。这项工作与NIA的战略重点非常一致，即研究如何在慢性病患者中促进健康和积极老龄化。

DESCRIPTION (provided by applicant): One-third of adults over 65 are obese. While previous studies have focused on promoting physical activity to reduce the health burdens of obesity and aging, physical activity levels have remained low among older adults and those with obesity. One explanation may be that the barriers to engaging in moderate intensity physical activity are too high for obese older adults (e.g. low physical function, pain, lack of motivation). At the same time, obese older adults spend over 10 hours per day sitting, more than any other age group. Emerging research now shows that sitting time has adverse health impacts, independent of meeting physical activity guidelines. Overcoming the barriers to reducing sedentary time may be a more feasible health-promoting behavior for obese older adults. Thus, we aim to explore a new approach to improving the health of obese older adults, who are at high risk for having or developing chronic health conditions, by focusing on reducing sedentary time. In our preliminary work, we developed procedures and intervention materials, showed reductions in sedentary time in a small one arm study, and established preliminary feasibility of our approach. The current randomized pilot study will formally assess the feasibility, acceptability, and impact of our innovative phone-based intervention designed to decrease sitting time and increase light intensity physical activity among sedentary obese older adults using a longer and more intensive intervention. We will compare the intervention to an attention-matched comparison group that receives a healthy aging education program (30 participants per group). Study outcomes, including sedentary time and sit-to-stand transitions (from activPAL inclinometers), light intensity physical activity (from accelerometers), and cardiovascular risk factor biomarkers will be measured at 12 weeks. If the intervention is feasible and shows promise for reducing sedentary time, we will plan a future randomized efficacy trial. In addition to reducing sedentary behavior, the long-term objective of this research is to create an effective intervention that will allow researchers to better understand the potential health impacts of reducing sitting among older and obese adults. To date, no such empirically validated interventions exist. As such, this formative research stands to make a unique and meaningful contribution to this field of research. This work is well-aligned with NIA's strategic focus on examining ways to promote healthy and active aging among those with chronic conditions.