De Pié y a Movernos Study: Promoting physical activity in older Latinx adults

De Pié y a Movernos 研究：促进拉丁裔老年人的身体活动

• 批准号: 10484730
• 负责人: Dori E Rosenberg
• 金额: $ 37.62万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-30 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10484730
• 关键词: Accelerometer; Acculturation; Adherence; Adult; Age; Alzheimer' s disease related dementia; Alzheimer' s disease risk; Cerebrovascular Circulation; Cognition; Cognitive; Communities; Control Groups; County; Dementia; Elderly; Exercise; Feedback; Goals; Growth; Guidelines; Habits; Health; Health Promotion; Hour; Hypertension; Impaired cognition; Individual; Intervention; Latina; Latinx; Latinx population; Measurement; Mediation; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Outcome; Participant; Persons; Phase; Physical activity; Population; Randomized; Randomized Controlled Trials; Recommendation; Reporting; Research; Research Personnel; Risk; Risk Factors; Self Efficacy; Social support; Target Populations; Testing; Theory of Change; Time; Translations; Work; aged; base; behavior change; brain health; cardiometabolism; comorbidity; dementia risk; design; exercise intervention; fitbit; high risk; human old age (65+); improved; innovation; intervention effect; meetings; middle age; moderate-to-vigorous physical activity; pandemic coronavirus; pilot test; prevent; primary outcome; psychosocial; recruit; secondary outcome; sedentary; sedentary lifestyle; sex; social; theories; treatment arm; white matter

SUMMARY Latinx older adults are at higher risk for developing Alzheimer’s Disease and Related Dementias (ADRD) than White older adults. Despite older Latinx adults having lower rates of physical activity (PA) and a high burden of comorbidities that are associated with ADRD, few studies have targeted this population with theory-based and culturally adapted approaches to reduce risk for ADRD. Building on pilot work by the team, the proposed project would allow us to culturally adapt a theory-based intervention to promote moderate-to-vigorous physical activity (MVPA) for Latinx adults ages 55 to 89 years. In Stage I (R61/Aim 1), we will finalize the recruitment and intervention strategy (including finalizing the target mechanisms of adherence to MVPA, initial cultural adaptation and translation) through meetings with our community advisory board and pilot testing with 10 Latinx adults. In Stage II (R33/Aim 2), we will randomize 130 Latinx adults to receive the 16-week, fully remote De Pié y a Movernos (De Pié) intervention or a control condition. The intervention will target the mechanisms of self-efficacy, PA habit strength, social support, and PA enjoyment using a staircase approach where participants will initially reduce their sitting by moving more to build confidence towards engaging in MVPA. Participants will also receive a Fitbit activity tracker, health coaching contacts, feedback on meeting goals, and will identify a support person. We will determine the effect of the De Pié intervention on activPAL accelerometer-based MVPA minutes/day (primary outcome) and adherence to meeting the MVPA guidelines of 150 minutes per week (secondary outcome). Further, mediation analyses will be conducted to determine the effect of the intervention on mechanisms of adherence (self-efficacy, habit strength, social support, enjoyment) and identify whether these mechanisms explain intervention effects on MVPA minutes/week and adherence to MVPA guidelines. We will explore cognition, acculturation, age and sex as moderators of these associations. Results will help identify important mechanisms of adherence to MVPA and inform culturally adapted, theory- based approaches to prevent ADRD in the Latinx community.

总结