Improving Childhood Growth and Development in Resource-Poor LMICs with Deworming

学龄前儿童是土壤传播致病的三大高危人群之一。 蠕虫感染(STH)。在这个年龄段，STH感染最重要的是蛔虫和鞭虫。 感染。世卫组织建议对12个月大的学龄前儿童进行驱虫，但没有 驱虫暴露的经验证据(根据使用时的年龄和频率 行政管理)对健康的影响最大。因此，本研究项目建议遵循以下原则 一组已知有不同驱虫暴露组蛋白的学龄前儿童 年龄在12到24个月之间。通过跟踪这些儿童直到五岁，累积健康 将对收益进行衡量，并确定最佳驱虫策略。预计这些健康 福利将延伸到儿童后期和以后。研究结果也将被用来指导驱虫 全球性病流行地区的卫生政策和战略。 相关性(请参阅说明)： 12至24个月龄之间存在着一个重要的机会之窗，此时健康和营养 干预措施在短期和长期健康方面都发挥着至关重要的作用。衡量这种健康状况是很重要的 影响，不仅因为它填补了一个研究空白，还因为它对计划是有用的反馈 经理和其他合伙人。在对五岁以下儿童进行跟踪调查时，这项队列研究将提供关键 RMF^irica！Ftvidenr.fi关于不同露水策略对健康的影响

Preschool-age children are one of the three high risk groups for morbidity attributable to soil-transmitted helminth infections (STH). At this age, the STH infections of most importance are Ascaris and Trichuris infections. WHO recommends deworming of preschool-age children as of 12 months of age, but there is no empirical evidence on what deworming exposure (in terms of age at administration adn frequency of administration) has the most beneficial impact on health. This research project therefore proposes to follow a cohort of preschool-age children who are known to have had different deworming exposure histones between 12 and 24 months of age. By following these children up to five years of age, cumulative health benefits will be measured and the optimal deworming strategy identified. It is expected that these health benefits will extend into later childhood and beyond. Research results will also be used to inform deworming health policy and strategies in STH-endemic regions globally. RELEVANCE (See instructions): An important window of opportunity exists between 12 and 24 months of age when health and nutrition interventions play a vital role in both short and long term health. It is important to measure this health impact, not only because it fills a research gap, but also because it is useful feedback for program managers, and other partners. In following children up to five years of age, this cohort study will provide key Rmf^irica! ftvidenr.fi on the health impact of different dewnrmina strateaifis tarafited to this high ri.sk ana