Potent Lipoglycopeptide Antibiotics Against C. Difficile

在一些人体内，艰难梭菌自然存在于肠道中。其他人在医院或疗养院就诊时，意外地摄入了这种细菌的孢子。有时，用于治疗感染的广谱抗生素也会杀死健康的肠道细菌。然后肠道中充满艰难梭菌，导致腹泻和疼痛，有时甚至死亡。我们将研究一种新的有效抗生素万卡匹林的使用，以杀死艰难梭菌并防止感染复发。

In some people C. difficile bacteria naturally reside in the gut. Other people accidentally ingest spores of the bacteria while they are patients in a hospital or nursing home. Sometimes, broad-spectrum antibiotics used to treat an infection also kill healthy gut bacteria. The gut then becomes overrun with C. difficile, causing diarrhoea and pain, and sometimes death. We will investigate the use of a new potent antibiotic, vancapticin, to kill C. difficle and prevent relapse of infection.