Next generation dengue diagnostics

下一代登革热诊断

• 批准号: LP100200504
• 负责人: Prof Matthew Cooper
• 金额: $ 15.93万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-02-23 至 2014-02-23
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP100200504
• 关键词: Next; generation; dengue; diagnostics

The 2009 dengue epidemic was widespread and the largest in North Queensland for 50 years. The outbreak was not quickly contained despite an extensive education program and a mosquito control taskforce. All four types of Dengue were detected, greatly increasing the chance of more severe complications such as Dengue haemorrhagic fever and Dengue shock syndrome. This project will improve our knowledge of Dengue proteins used in tests to diagnose the virus. The new knowledge will be used to develop an easy to use test to diagnose Dengue infection early, rapidly and accurately. Effective diagnosis of Dengue will then allow timely implementation of intervention strategies (mosquito control, public advice, isolation and care).

2009年的登革热疫情很普遍，是北昆士兰50年来最大的一次。尽管开展了广泛的教育项目，并成立了蚊虫控制工作组，但疫情并未迅速得到控制。所有四种登革热都被发现，大大增加了登革出血热和登革休克综合征等更严重并发症的机会。该项目将提高我们对用于诊断该病毒的测试的登革热蛋白的认识。这些新知识将用于开发一种易于使用的检测方法，以便早期、快速和准确地诊断登革热感染。然后，对登革热的有效诊断将允许及时实施干预战略（蚊虫控制、公众咨询、隔离和护理）。