Altering the microbiome to treat COPD

改变微生物组来治疗慢性阻塞性肺病

• 批准号: nhmrc : GNT1059239
• 负责人: Prof Matthew Cooper
• 金额: $ 117.96万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/altering-microbiome-treat-copd/1344683
• 关键词: Altering; microbiome; treat; COPD

Smoking leads to lung inflammation that causes emphysema - a major health problem in Australia. Emphysema progressively declines even if smoking stops and there are no treatments. Recently changes in gut microbes have been linked to inducing or protecting against inflammation in the gut and lung. Thus we may be able to control inflammation by modifying these gut microbiomes. We may be able to ingest specific microbes or use specific antibiotics or other factors as new treatments for emphysema.

吸烟导致肺部炎症，导致肺气肿-一个主要的健康问题，在澳大利亚。即使戒烟，肺气肿也会逐渐减少，而且没有治疗方法。最近，肠道微生物的变化与诱导或保护肠道和肺部炎症有关。因此，我们可以通过改变这些肠道微生物来控制炎症。我们也许能够摄取特定的微生物或使用特定的抗生素或其他因素作为肺气肿的新疗法。