Preclinical validation of oxytocin as a novel treatment for alcohol dependence

催产素作为酒精依赖新疗法的临床前验证

• 批准号: nhmrc : 1011518
• 负责人: A/Pr Glenn Hunt
• 金额: $ 34.52万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/preclinical-validation-oxytocin-alcohol-dependence/109597
• 关键词: Preclinical; validation; oxytocin; novel; treatment

Alcohol dependence is a major cause of mental and physical illness in Australia. Current medications for treating this condition are of limited effectiveness. This project will investigate the ability of the hormone oxytocin to reduce alcohol abuse and alcohol craving and to reverse the brain damage that alcohol causes. The project will also develop new medications, based on oxytocin, but with more powerful and longer lasting effects. These medications may provide a breakthrough in the fight against alcoholism.

酒精依赖是澳大利亚精神和身体疾病的一个主要原因。目前治疗这种疾病的药物效果有限。该项目将调查催产素在减少酒精滥用和酒精渴望以及逆转酒精引起的脑损伤方面的能力。该项目还将开发新的药物，以催产素为基础，但效果更强、更持久。这些药物可能会在与酗酒的斗争中取得突破。