Randomised controlled trial of HPV self-sampling for improving participation in cervical screening: the iPAP trial

HPV 自我采样提高宫颈筛查参与度的随机对照试验：iPAP 试验

• 批准号: nhmrc : 1045346
• 负责人: A/Pr Dorota Gertig
• 金额: $ 35.64万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/randomised-controlled-trial-ipap-trial/111739
• 关键词: Randomised; controlled; trial; HPV; self

Effectiveness of cervical cancer screening relies on maximising participation. Unlike a Pap test, an HPV test may be self-collected and this may overcome some of the barriers to Pap testing. Overseas trials have found higher uptake for HPV self-sampling (between 3-30%) compared with Pap test reminder letters. We will conduct the first randomised trial in Australia comparing home-based HPV self-sampling with a reminder letter, to evaluate whether this improves participation and followup.

宫颈癌筛查的有效性取决于最大限度的参与。与巴氏试验不同，HPV检测可以自我收集，这可能会克服巴氏试验的一些障碍。海外试验发现，与巴氏试验提醒信相比，HPV自我采样的吸收率更高（3-30%）。我们将在澳大利亚进行第一项随机试验，比较家庭HPV自我采样与提醒信，以评估这是否会改善参与和随访。