Single-molecule view of actin-tropomyosin filament dynamics

肌动蛋白-原肌球蛋白丝动力学的单分子视图

• 批准号: DP130100936
• 负责人: Prof Till Boecking
• 金额: $ 22.81万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-04-01
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP130100936
• 关键词: Single; molecule; view; actin; tropomyosin

This project aims to develop a microscopy platform to resolve how filaments of the cytoskeleton, the cell's internal scaffolding, are assembled. This technology will then be used to understand how drugs can target specific components and functions of the cytoskeleton that are hijacked in cancer cells.

该项目旨在开发一个显微镜平台，以解决细胞骨架(细胞内部支架)的细丝是如何组装的。然后，这项技术将被用来理解药物如何针对被劫持在癌细胞中的细胞骨架的特定成分和功能。