RCAN1 IS A MASTER REGULATOR OF BETA CELL FUNCTION AND INSULIN SECRETION
RCAN1 IS A MASTER REGULATOR OF BETA CELL FUNCTION AND INSULIN SECRETION
批准号:
nhmrc : 1008816
负责人:
Prof Damien Keating
金额:
$29.78万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Type 2 diabetes affects over 1.5 million Australians and is caused by insufficient insulin release by beta cells in the pancreas. We have discovered a new regulator of insulin secretion called RCAN1 and we now aim to understand how this regulation occurs. We also believe RCAN1 may be responsible for the transition from healthy to dysfunctional beta cell in Type 2 diabetes and this project will identify whether this is the case.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Defining how serotonin regulates gut motility
-
批准号:DP190103525
-
项目类别:Discovery Projects
-
资助金额:$37.14万
-
财政年份:2019
-
负责人:Prof Damien Keating
-
依托单位:
Targeting RCAN1 to treat type 2 diabetes and obesity
-
批准号:nhmrc : 1142403
-
项目类别:Project Grants
-
资助金额:$55.07万
-
财政年份:2018
-
负责人:Prof Damien Keating
-
依托单位:
Mechanisms controlling enteroendocrine hormone secretion in human duodenum
-
批准号:LP150100419
-
项目类别:Linkage Projects
-
资助金额:$25.55万
-
财政年份:2016
-
负责人:Prof Damien Keating
-
依托单位:
Defining the mechanisms that control exocytosis and cell signalling in health and disease.
-
批准号:nhmrc : GNT1088737
-
项目类别:Career Development Fellowships
-
资助金额:$45.55万
-
财政年份:2015
-
负责人:Prof Damien Keating
-
依托单位:
Defining the mechanisms that control exocytosis and cell signalling in health and disease.
-
批准号:nhmrc : 1088737
-
项目类别:Career Development Fellowships
-
资助金额:$31.57万
-
财政年份:2015
-
负责人:Prof Damien Keating
-
依托单位:
Understanding the vesicle release mechanisms that regulate peripheral serotonin levels
-
批准号:DP130101189
-
项目类别:Discovery Projects
-
资助金额:$31.79万
-
财政年份:2013
-
负责人:Prof Damien Keating
-
依托单位:
Huntingtin-associated protein 1 controls cell communication.
-
批准号:DP110105101
-
项目类别:Discovery Projects
-
资助金额:$18.24万
-
财政年份:2011
-
负责人:Prof Damien Keating
-
依托单位:
Identifying novel roles of disease-related proteins in the regulation of exocytosis and nervous communication.
-
批准号:FT0990901
-
项目类别:ARC Future Fellowships
-
资助金额:$48.96万
-
财政年份:2010
-
负责人:Prof Damien Keating
-
依托单位:
The role of Down syndrome candidate region 1 (DSCR1) in neurotransmitter release, vesicle recycling and Down syndrome.
-
批准号:nhmrc : 441112
-
项目类别:NHMRC Project Grants
-
资助金额:$23.49万
-
财政年份:2007
-
负责人:Prof Damien Keating
-
依托单位:
国内基金
海外基金
超对称可积系统:master对称、Cartan-Maurer方程
-
批准号:11505284
-
项目类别:青年科学基金项目
-
资助金额:18.0万元
-
批准年份:2015
-
负责人:田凯
-
依托单位: