Defining the mechanisms that control exocytosis and cell signalling in health and disease.

定义健康和疾病中控制胞吐作用和细胞信号传导的机制。

• 批准号: nhmrc : GNT1088737
• 负责人: Prof Damien Keating
• 金额: $ 45.55万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/defining-mechanisms-control-health-disease/1345749
• 关键词: Defining; mechanisms; control; exocytosis; cell

This research focuses on pathways regulating nervous communication and hormone release. It centres on proteins that regulate this process and on the function of specific endocrine cells in health and disease. It uses unique research tools developed in this laboratory enabling the study of mechanisms regulating cell signalling. Through this research I aim to identify how the cells in our body communicate with each other and how this relates to diseases such as type 2 diabetes.

这项研究的重点是调节神经通讯和激素释放的途径。它集中于调节这一过程的蛋白质以及健康和疾病中特定内分泌细胞的功能。它使用该实验室开发的独特研究工具，能够研究调节细胞信号传导的机制。通过这项研究，我的目标是确定我们体内的细胞如何相互交流，以及这与2型糖尿病等疾病的关系。