Identifying novel roles of disease-related proteins in the regulation of exocytosis and nervous communication.

识别疾病相关蛋白在胞吐作用和神经通讯调节中的新作用。

• 批准号: FT0990901
• 负责人: Prof Damien Keating
• 金额: $ 48.96万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT0990901
• 关键词: Identifying; novel; roles; disease; related

This research aims to identify new molecules involved in regulating nerve communication and hormone secretion and which are relevent to human diseases and conditions including Type 2 Diabetes, Down Syndrome, Alzheimer's Disease and Huntington's Disease. The findings may provide new targets in the treatments of such conditions. This research is therefore of special relevance to National Research Priority 2: Promoting and Maintaining Good Health and especially to the sub-areas of this Research Priority 2: Ageing well, ageing productively and Preventative healthcare.

这项研究旨在确定参与调节神经通讯和激素分泌的新分子，这些分子与人类疾病和病症有关，包括2型糖尿病，唐氏综合症，阿尔茨海默病和亨廷顿病。这些发现可能为治疗此类疾病提供新的靶点。因此，这项研究与国家研究重点2：促进和保持良好健康特别相关，特别是与本研究重点2的子领域：老龄化良好，老龄化富有成效和预防性医疗保健。