Redefining Tissue-Resident Memory T cells

重新定义组织驻留记忆 T 细胞

• 批准号: nhmrc : GNT1129711
• 负责人: Dr Laura Mackay
• 金额: $ 43.91万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/redefining-tissue-resident-t-cells/1347768
• 关键词: Redefining; Tissue; Resident; Memory; cells

We have identified a population of immune cells called ‘resident memory T cells’ that reside in tissues of the body. These resident memory T cells play an important role in controlling infections, but it is also apparent that they can lead to aberrant immune reactions, causing autoimmune diseases. This project aims to further our understanding of these immune cells, including how they can be identified and generated, and how they can be controlled to prevent disease.

我们已经确定了一群被称为“常驻记忆T细胞”的免疫细胞，它们驻留在身体的组织中。这些常驻记忆T细胞在控制感染中起着重要作用，但也很明显，它们可以导致异常的免疫反应，引起自身免疫性疾病。该项目旨在进一步加深我们对这些免疫细胞的理解，包括如何识别和产生它们，以及如何控制它们以预防疾病。