Regulation of Tissue-Resident Memory T cell Development

组织驻留记忆 T 细胞发育的调节

• 批准号: nhmrc : GNT1083685
• 负责人: Dr Laura Mackay
• 金额: $ 31.87万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/regulation-tissue-resident-cell-development/1345521
• 关键词: Regulation; Tissue; Resident; Memory; cell

A recently identified subset of T cells that reside in the skin are critical to combat viral infection. However, little is known about how these T cell populations are formed. This project will characterise the pathways required to generate these cells and will identify novel factors that regulate their development. A greater understanding of how these T cells can be generated will open the way to utilise these cells in new vaccine strategies.

最近发现的一种存在于皮肤中的T细胞亚群对对抗病毒感染至关重要。然而，人们对这些T细胞群是如何形成的知之甚少。该项目将描述产生这些细胞所需的途径，并将确定调节其发育的新因素。更深入地了解这些T细胞是如何产生的，将为在新的疫苗策略中利用这些细胞开辟道路。