An integrated model of environmental, neurodevelopmental, and epigenetic resistance and responsiveness to early intervention in childhood psychopathology.

心理健康问题的基础在生命早期就存在。该项目将对接受以家庭环境质量为目标的干预的有常见心理健康问题的儿童样本的稳定性和变化进行绘图。它将制定一份路线图，说明儿童的长处和弱点如何受到治疗的影响，防止未来出现精神健康问题，并为未能从现有治疗中受益的儿童提出新的干预目标。

The foundations of mental health problems are present early in life. This project will map stability and change in a sample of children with common mental health problems receiving an intervention targeting the quality of the home environment. It will produce a road map of how the child’s strengths and vulnerabilities are affected by treatment, protect against future mental health problems, and suggest new intervention targets for children who fail to benefit from existing treatments.