The current multidrug resistant Escherichia coli pandemic: exploring novel therapies against the predominant culprit E. coli ST131.
The current multidrug resistant Escherichia coli pandemic: exploring novel therapies against the predominant culprit E. coli ST131.
批准号:
nhmrc : 1069370
负责人:
Prof Mark Schembri
金额:
$34.16万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2017-12-31
中文摘要
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英文摘要
Escherichia coli ST131 is a pandemic superbug. Like MRSA, E. coli ST131 infections are resistant to multiple antibiotics and can become life threatening. This study will show how adhesion can be the 'Achilles' heel' of this global pathogen and how blocking E. coli ST131 adhesion offers an alternative therapy for multidrug resistant human infections. As we are left with no effective antimicrobials to treat E. coli ST131 infections, this work will provide novel outcomes that are sorely needed.
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国内基金
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