The generation, fate and functional potential of recent thymic emigrants

一种特殊的白色血细胞，称为T淋巴细胞，负责控制我们对外来入侵者的免疫反应。这些细胞在胸腺中发育，在那里它们学会区分外来入侵者和自身组织，然后迁移到其他器官。这个过程的调节对于维持体内的T淋巴细胞池很重要。重要的是，T淋巴细胞不对自身组织产生反应，因为这会导致一种称为自身免疫的自毁性疾病。由于这些发育中的T淋巴细胞在胸腺中不会看到所有种类的自身组织，我们建议在它们离开胸腺后，它们的教育可以继续一段时间，以防止自身组织反应。

A particular kind of white blood cell, called a T lymphocyte, is responsible for controlling our immune responses to foreign invaders. These cells develop in the thymus, where they learn to distinguish between foreign invaders and self tissue, before emigrating to other organs. The regulation of this process is important to maintain a pool of T lymphocytes in the body. It is important that T lymphocytes do not respond against self tissue, as this can lead to a Oself destructO disease called autoimmunity. Since these developing T lymphocytes will not see all kinds of self tissue while in the thymus, we propose that their education to prevent self-tissue reactivity may continue for some time after they leave the thymus.