A Brain-Based Measure of Anxiety Sensitivity: Validation of a Novel Intermediate Phenotype with Psychophysiologically-Informed Neuroimaging

基于大脑的焦虑敏感性测量：通过心理生理学神经影像学验证新型中间表型

• 批准号: nhmrc : 1025619
• 负责人: A/Pr Alexander Fornito
• 金额: $ 18.13万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/brain-based-measure-informed-neuroimaging/110441
• 关键词: Brain; Based; Measure; Anxiety; Sensitivity

Excessive anxiety is disabling, such that people who suffer from a clinical anxiety disorder are often crippled by overwhelming emotional and physical symptoms. We will use sophisticated brain imaging technology to understand how certain brain areas produce feelings of anxiety, including a common fear of arousal related bodily sensations. This work is expected to enhance our basic understanding of the brain basis of anxiety symptoms and may inform new treatment options with biological rationale.

过度的焦虑是致残的，比如患有临床焦虑症的人经常被压倒性的情绪和身体症状所困扰。我们将使用复杂的大脑成像技术来了解某些大脑区域如何产生焦虑感，包括对与身体感觉有关的唤醒的常见恐惧。这项工作有望增强我们对焦虑症状的大脑基础的基本理解，并可能为新的治疗方案提供生物学依据。