Cognitive control and brain connectivity disturbances in schizophrenia and obsessive-compulsive: Clarifying their nature, specificity, and consequences

精神分裂症和强迫症的认知控制和大脑连接障碍：阐明其性质、特异性和后果

• 批准号: nhmrc : 1008921
• 负责人: A/Pr Alexander Fornito
• 金额: $ 33.23万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cognitive-control-brain-specificity-consequences/109357
• 关键词: Cognitive; control; brain; connectivity; disturbances

Deficits of behavioural control are chronic and debilitating features of both schizophrenia and OCD. As behavioural control depends on activity within many key regions of the brain, these deficits may result not only from dysfunction within one or more region, but also from abnormal interactions between them. By studying how the activity in one region depends on another, and comparing findings between disorders, a better understanding of brain function in schizophrenia and OCD can be established

行为控制缺陷是精神分裂症和强迫症的慢性和衰弱特征。由于行为控制取决于大脑许多关键区域的活动，这些缺陷不仅可能是由于一个或多个区域的功能障碍，而且可能是由于它们之间的异常相互作用。通过研究一个区域的活动如何依赖于另一个区域，并比较不同疾病之间的结果，可以更好地了解精神分裂症和强迫症的大脑功能