The molecular basis of experimental oxygen-induced retinopathy

实验性氧诱导视网膜病变的分子基础

• 批准号: nhmrc : 480481
• 负责人: Miss Melinda Tea
• 金额: $ 5.53万
• 依托单位: Flinders University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Postgraduate Scholarships
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-basis-experimental-induced-retinopathy/115389
• 关键词: molecular; basis; experimental; oxygen; induced

Retinopathy of prematurity is a potentially blinding eye disease that affects some very low birth-weight premature infants given oxygen therapy. Determining which infants are likely to be severely affected is currently difficult. Using an experimental animal model, the aim of this project is to investigate genetic factors that may be used to identify those infants who are most at risk of developing disabling retinopathy.

早产儿视网膜病变是一种潜在的致盲性眼病，影响到一些给予氧疗的极低出生体重早产儿。目前很难确定哪些婴儿可能受到严重影响。使用实验动物模型，该项目的目的是调查遗传因素，可用于确定那些婴儿谁是最危险的发展致残性视网膜病变。