The mode of action of the haem protein neuroglobin in protecting nerve cells

血红素神经红蛋白保护神经细胞的作用方式

• 批准号: DP130103711
• 负责人: Prof Paul Witting
• 金额: $ 18.82万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-02-08 至 2016-02-08
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP130103711
• 关键词: mode; action; haem; protein; neuroglobin

Outcomes from this project will assist in developing new treatments for stroke and chronic degenerative brain disorders by characterising how the haem protein neuroglobin protects neurons of the central and peripheral nervous system from oxidative damage. This project will also develop pharmacological strategies to boost the concentration of neuroglobin in neurons.

该项目的成果将有助于通过表征血红素蛋白神经红蛋白如何保护中枢和外周神经系统的神经元免受氧化损伤来开发中风和慢性退行性脑疾病的新疗法。该项目还将开发药理学策略，以提高神经元中脑红蛋白的浓度。