Equipment for impedance cardiography and behavior analysis

阻抗心动图和行为分析设备

• 批准号: 344734-2007
• 负责人: Haley, David
• 金额: $ 1.78万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2006
• 资助国家: 加拿大
• 起止时间: 2006-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=325776
• 关键词: Equipment; impedance; cardiography; behavior; analysis

Stress hormones have the capacity to enhance or disrupt the brain's capacity to form new memories, especially under conditions of emotional arousal. Over the past few decades, there has been much progress in our understanding of age-related changes in memory, and, more recently, in the neural correlates of memory development. In contrast, there is sparse knowledge on how stress hormones affect memory in infants or on the hormonal correlates of memory development. My research program addresses these gaps by investigating the relationship between stress and memory in the first year of life. I use age-appropriate methods to study stress, emotion, and memory and have adopted a research design that differentiates the effects of stress on specific stages of memory (i.e., encoding, consolidation, and retrieval). I am testing the hypothesis that moderate stress enhances memory. I am also examining the role of emotion in learning and memory by testing the hypothesis that more frequent expressions of anger rather than sadness during stress is associated with a pattern of stress reactivity that enhances memory consolidation. A third question that my research program addresses is sex differences in the relationship between stress and memory. Based on animal studies, I am testing the hypothesis that the impact of stress on memory differs in boys and girls. Finally, I am evaluating normal developmental changes in stress hormones over the first year in order to determine whether these changes predict memory performance. This novel approach to the study of stress in infants is advancing our understanding of how stress affects cognition, and it offers critical insight into how children's ability to regulate stress affects their ability to remember what they have learned. This research program will significantly enhance our knowledge of the role of stress in memory during infancy, thus laying crucial groundwork for evidence-based practices in pediatric health care, parenting, and early education policy.

压力荷尔蒙有能力增强或破坏大脑形成新记忆的能力，尤其是在情绪激动的情况下。在过去的几十年里，我们对与年龄相关的记忆变化的理解有了很大的进展，最近，在记忆发展的神经相关方面也有了很大的进展。相比之下，关于应激激素如何影响婴儿的记忆，以及与记忆发展相关的激素，我们知之甚少。我的研究项目通过调查一岁的压力和记忆之间的关系来解决这些空白。我使用适合年龄的方法来研究压力、情绪和记忆，并采用了一种研究设计，区分压力对记忆的特定阶段（即编码、巩固和检索）的影响。我在测试适度压力能增强记忆力的假设。我也在研究情绪在学习和记忆中的作用，通过验证这样一个假设，即在压力下更频繁地表达愤怒而不是悲伤，与一种增强记忆巩固的压力反应模式有关。我的研究项目要解决的第三个问题是压力和记忆之间关系的性别差异。基于动物研究，我正在测试一个假设，即压力对记忆的影响在男孩和女孩中是不同的。最后，我正在评估第一年压力激素的正常发育变化，以确定这些变化是否能预测记忆表现。这种研究婴儿压力的新方法正在推进我们对压力如何影响认知的理解，它为儿童调节压力的能力如何影响他们记忆所学知识的能力提供了重要的见解。这一研究项目将显著提高我们对婴儿时期压力在记忆中的作用的认识，从而为儿科保健、育儿和早期教育政策的循证实践奠定重要基础。