Characterisation of an antigen presenting cell unique to spleen

脾脏特有的抗原呈递细胞的表征

• 批准号: nhmrc : 585443
• 负责人: Prof Helen O'Neill
• 金额: $ 28.05万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterisation-an-antigen-unique-spleen/81345
• 关键词: Characterisation; antigen; presenting; cell; unique

The body depends on a range of defence mechanisms to remove invaders that enter by various routes. Antigen presenting cells are central to immunity in that they engulf and destroy dead cells and pathogens and present pieces of those pathogens or 'antigens' to white blood cells called T and B lymphocytes. These cells then start to fight the infection or disease. A new type of antigen presenting cell will be investigated for its particular ability to arrest blood-borne pathogens and disease.

身体依靠一系列防御机制来清除通过各种途径进入的入侵者。抗原呈递细胞是免疫的核心，因为它们吞噬和破坏死细胞和病原体，并将这些病原体或“抗原”的碎片呈递给称为T和B淋巴细胞的白色血细胞。然后这些细胞开始对抗感染或疾病。一种新型的抗原提呈细胞将被研究其特殊的能力，以阻止血液传播的病原体和疾病。