Characterisation of the key role played by the persistent phase of Chlamydia pneumoniae in disease pathogenesis

肺炎衣原体持续期在疾病发病机制中所起关键作用的表征

• 批准号: nhmrc : 199908
• 负责人: Prof Peter Timms
• 金额: $ 19.09万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2002
• 资助国家: 澳大利亚
• 起止时间: 2002-01-01 至 2004-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterisation-key-role-disease-pathogenesis/98917
• 关键词: Characterisation; key; role; played; persistent

Chlamydia pneumoniae is a relatively newly identified pathogen that is responsible for several respiratory conditions such as, pneumonia and chronic obstructive pulmonary disease and has been strongly linked to heart disesae. Serious disease is due to low grade chronic infections, but we do not understand how the bacterium causes these chronic diseases. This project will identify markers of chronic C. pneumoniae infections and relate these to the disease that results. Identifying these markers of chronic disease should lead to improved methods of disease control, including new diagnostic tests, vaccines and new drug therapies.

肺炎衣原体是一种相对较新发现的病原体，它可引起多种呼吸道疾病，如肺炎和慢性阻塞性肺病，并与心脏病密切相关。严重的疾病是由于低度慢性感染，但我们不知道细菌是如何导致这些慢性疾病的。该项目将确定慢性丙型肝炎的标志物。肺炎感染，并将其与导致的疾病联系起来。确定这些慢性病的标志物应该会导致疾病控制方法的改进，包括新的诊断测试，疫苗和新的药物疗法。