Characterisation of Porphyromonas gingivalis and Treponema denticola interactions in the development of a pathogenic biofilm

牙龈卟啉单胞菌和齿垢密螺旋体在致病性生物膜形成过程中相互作用的表征

• 批准号: nhmrc : GNT1083600
• 负责人: Prof Eric Reynolds
• 金额: $ 36.57万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/characterisation-porphyromonas-gingivalis-pathogenic-biofilm/1345518
• 关键词: Characterisation; Porphyromonas; gingivalis; Treponema; denticola

Gum disease (periodontitis) is an inflammatory disease caused by bacterial pathogens that is the major cause of tooth loss in adults. It is also associated with systemic diseases such as cardiovascular disease. In this study we will determine the mechanisms by which two bacterial species work together to produce the pathogenic dental plaque that causes disease.

牙周病(牙周炎)是一种由细菌病原体引起的炎症性疾病，是成年人牙齿脱落的主要原因。它还与心血管疾病等系统性疾病有关。在这项研究中，我们将确定两种细菌共同作用产生致病牙菌斑的机制。